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Rationally Improving Doramectin Production in Industrial Streptomyces avermitilis Strains
Avermectins (AVMs), a family of 16-membered macrocyclic macrolides produced by Streptomyces avermitilis, have been the most successful microbial natural antiparasitic agents in recent decades. Doramectin, an AVM derivative produced by S. avermitilis bkd(−) mutants through cyclohexanecarboxylic acid...
Autores principales: | Dang, Fujun, Xu, Qingyu, Qin, Zhongjun, Xia, Haiyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295569/ https://www.ncbi.nlm.nih.gov/pubmed/37370670 http://dx.doi.org/10.3390/bioengineering10060739 |
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