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Rationally Improving Doramectin Production in Industrial Streptomyces avermitilis Strains

Avermectins (AVMs), a family of 16-membered macrocyclic macrolides produced by Streptomyces avermitilis, have been the most successful microbial natural antiparasitic agents in recent decades. Doramectin, an AVM derivative produced by S. avermitilis bkd(−) mutants through cyclohexanecarboxylic acid...

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Detalles Bibliográficos
Autores principales: Dang, Fujun, Xu, Qingyu, Qin, Zhongjun, Xia, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295569/
https://www.ncbi.nlm.nih.gov/pubmed/37370670
http://dx.doi.org/10.3390/bioengineering10060739

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