Cargando…

Deletion of the CD2 Gene in the Virulent ASFV Congo Strain Affects Viremia in Domestic Swine, but Not the Virulence

SIMPLE SUMMARY: African swine fever (ASF) causes serious economic losses to the global pig industry. Unfortunately, there is currently no effective and safe vaccine, although its development is actively continuing. To date, experimental vaccines based on the use of live attenuated strains of the ASF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koltsov, Andrey, Krutko, Sergey, Kholod, Natalia, Sukher, Mikhail, Belov, Sergey, Korotin, Alexey, Koltsova, Galina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295570/ https://www.ncbi.nlm.nih.gov/pubmed/37370512 http://dx.doi.org/10.3390/ani13122002

Ejemplares similares

Comparison of Attenuated and Virulent Strains of African Swine Fever Virus Genotype I and Serogroup 2
por: Kholod, Natalia, et al.
Publicado: (2023)

Growth Kinetics and Protective Efficacy of Attenuated ASFV Strain Congo with Deletion of the EP402 Gene
por: Koltsova, Galina, et al.
Publicado: (2021)

Isolation and Characterization of Swinepox Virus from Outbreak in Russia
por: Koltsov, Andrey, et al.
Publicado: (2023)

Analysis of gene expression in monocytes of immunized pigs after infection with homologous or heterologous African swine fever virus
por: Kholod, Natalia, et al.
Publicado: (2022)

ASFV Gene A151R Is Involved in the Process of Virulence in Domestic Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

Deletion of the ASFV dUTPase Gene E165R from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs
por: Vuono, Elizabeth A., et al.
Publicado: (2022)

Evaluation of an ASFV RNA Helicase Gene A859L for Virus Replication and Swine Virulence
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2021)

Evaluation of the Function of ASFV Gene E66L in the Process of Virus Replication and Virulence in Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2023)

Assessment of African swine fever vaccine candidate ASFV-G-∆MGF in a reversion to virulence study
por: Deutschmann, Paul, et al.
Publicado: (2023)

Evaluation of the Function of the ASFV KP177R Gene, Encoding for Structural Protein p22, in the Process of Virus Replication and in Swine Virulence
por: Vuono, Elizabeth A., et al.
Publicado: (2021)

The low-virulent African swine fever virus (ASFV/NH/P68) induces enhanced expression and production of relevant regulatory cytokines (IFNα, TNFα and IL12p40) on porcine macrophages in comparison to the highly virulent ASFV/L60
por: Gil, S., et al.
Publicado: (2008)

Deletion of African swine fever virus interferon inhibitors from the genome of a virulent isolate reduces virulence in domestic pigs and induces a protective response
por: Reis, Ana Luisa, et al.
Publicado: (2016)

The African Swine Fever Isolate ASFV-Kenya-IX-1033 Is Highly Virulent and Stable after Propagation in the Wild Boar Cell Line WSL
por: Hemmink, Johanneke D., et al.
Publicado: (2022)

Deletion of the CD2v Gene from the Genome of ASFV-Kenya-IX-1033 Partially Reduces Virulence and Induces Protection in Pigs
por: Hemmink, Johanneke D., et al.
Publicado: (2022)

Usability of Immortalized Porcine Kidney Macrophage Cultures for the Isolation of ASFV without Affecting Virulence
por: Kameyama, Ken-ichiro, et al.
Publicado: (2022)

Patterns of ASFV Transmission in Domestic Pigs in Serbia
por: Glišić, Dimitrije, et al.
Publicado: (2023)

Immunobiological Characteristics of the Attenuated African Swine Fever Virus Strain Katanga-350
por: Sereda, Alexey D., et al.
Publicado: (2022)

The Presence of Virus Neutralizing Antibodies Is Highly Associated with Protection against Virulent Challenge in Domestic Pigs Immunized with ASFV live Attenuated Vaccine Candidates
por: Silva, Ediane B., et al.
Publicado: (2022)

Inoculation with ASFV-Katanga-350 Partially Protects Pigs from Death during Subsequent Infection with Heterologous Type ASFV-Stavropol 01/08
por: Vlasov, Mikhail E., et al.
Publicado: (2023)

Deletion of the EP296R Gene from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs
por: Vuono, Elizabeth A., et al.
Publicado: (2022)

African Swine Fever Virus (ASFV): Immunity and Vaccine Development
por: Chathuranga, Kiramage, et al.
Publicado: (2023)

An AIDS-Denialist Online Community on a Russian Social Networking Service: Patterns of Interactions With Newcomers and Rhetorical Strategies of Persuasion
por: Meylakhs, Peter, et al.
Publicado: (2014)

Development of a Dual ELISA for the Detection of CD2v-Unexpressed Lower-Virulence Mutational ASFV
por: Lv, Changjie, et al.
Publicado: (2021)

Differential Effect of the Deletion of African Swine Fever Virus Virulence-Associated Genes in the Induction of Attenuation of the Highly Virulent Georgia Strain
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2019)

Cytokine Storm in Domestic Pigs Induced by Infection of Virulent African Swine Fever Virus
por: Wang, Shuchao, et al.
Publicado: (2021)

Deletion of the H240R Gene in African Swine Fever Virus Partially Reduces Virus Virulence in Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2023)

Stability of African Swine Fever Virus in Carcasses of Domestic Pigs and Wild Boar Experimentally Infected with the ASFV “Estonia 2014” Isolate
por: Fischer, Melina, et al.
Publicado: (2020)

Subsequent Immunization of Pigs with African Swine Fever Virus (ASFV) Seroimmunotype IV Vaccine Strain FK-32/135 and by Recombinant Plasmid DNA Containing the CD2v Derived from MK-200 ASFV Seroimmunotype III Strain Does Not Protect from Challenge with ASFV Seroimmunotype III
por: Sereda, Alexey D., et al.
Publicado: (2023)

African Swine Fever Vaccine Candidate ASFV-G-ΔI177L Produced in the Swine Macrophage-Derived Cell Line IPKM Remains Genetically Stable and Protective against Homologous Virulent Challenge
por: Borca, Manuel V., et al.
Publicado: (2023)

The attenuated ASFV strains MK-200 and FK-32/135 as possible models for investigation of protective immunity by ASFV infection
por: Sereda, Alexey D., et al.
Publicado: (2022)

Regulation of antiviral immune response by African swine fever virus (ASFV)
por: Zheng, Xiaojie, et al.
Publicado: (2022)

Detection and genetic characterization of African swine fever virus (ASFV) in clinically infected pigs in two districts in South Kivu province, Democratic Republic Congo
por: Bisimwa, Patrick N., et al.
Publicado: (2021)

Seroimmunotyping of African swine fever virus
por: Sereda, Alexey D., et al.
Publicado: (2023)

Development of a fluorescent ASFV strain that retains the ability to cause disease in swine
por: Borca, Manuel V., et al.
Publicado: (2017)

Deletion at the 5’-end of Estonian ASFV strains associated with an attenuated phenotype
por: Zani, Laura, et al.
Publicado: (2018)

Deletion of African Swine Fever Virus Histone-like Protein, A104R from the Georgia Isolate Drastically Reduces Virus Virulence in Domestic Pigs
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

Capsid-Specific Antibody Responses of Domestic Pigs Immunized with Low-Virulent African Swine Fever Virus
por: Tng, Priscilla Y. L., et al.
Publicado: (2023)

ASF Vaccine Candidate ASFV-G-∆I177L Does Not Exhibit Residual Virulence in Long-Term Clinical Studies
por: Borca, Manuel V., et al.
Publicado: (2023)

X69R Is a Non-Essential Gene That, When Deleted from African Swine Fever, Does Not Affect Virulence in Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2020)

Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine
por: Borca, Manuel V., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ser9reo89mocgitn6psnmoorah