Diagnosis of Periprosthetic Joint Infection: The Utility of Biomarkers in 2023

Periprosthetic joint infection (PJI) is a rare yet devastating complication following total joint arthroplasty (TJA). Early and accurate diagnosis of PJI is paramount in order to maximize the chances of successful treatment. However, we are yet to identify a single “gold standard” test for the diagn...

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Detalles Bibliográficos
Autores principales: Yilmaz, Mehmet Kursat, Abbaszadeh, Ahmad, Tarabichi, Saad, Azboy, Ibrahim, Parvizi, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295740/
https://www.ncbi.nlm.nih.gov/pubmed/37370373
http://dx.doi.org/10.3390/antibiotics12061054
Descripción
Sumario:Periprosthetic joint infection (PJI) is a rare yet devastating complication following total joint arthroplasty (TJA). Early and accurate diagnosis of PJI is paramount in order to maximize the chances of successful treatment. However, we are yet to identify a single “gold standard” test for the diagnosis of PJI. As a result, the diagnosis of PJI is often challenging. Currently, the 2018 ICM definition of PJI is the only validated diagnostic criteria available. This article will review the importance of serum and synovial biomarkers in the diagnosis of PJI. In addition, it will provide a brief overview of the emerging modalities for the identification of infections in this setting.

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