SerpinB3 Upregulates Low-Density Lipoprotein Receptor-Related Protein (LRP) Family Members, Leading to Wnt Signaling Activation and Increased Cell Survival and Invasiveness

SIMPLE SUMMARY: The Wnt-β-catenin signaling regulates liver homeostasis and repair in adulthood, while its abnormal regulation is involved in the development of several chronic diseases and tumors. SerpinB3 has been shown to induce β-catenin, and both molecules are overexpressed in tumors, particula...

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Detalles Bibliográficos
Autores principales: Quarta, Santina, Cappon, Andrea, Turato, Cristian, Ruvoletto, Mariagrazia, Cannito, Stefania, Villano, Gianmarco, Biasiolo, Alessandra, Maggi, Maristella, Protopapa, Francesca, Bertazza, Loris, Fasolato, Silvano, Parola, Maurizio, Pontisso, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295789/
https://www.ncbi.nlm.nih.gov/pubmed/37372056
http://dx.doi.org/10.3390/biology12060771

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