Myelin oligodendrocyte glycoprotein antibody-associated encephalitis after severe acute respiratory syndrome coronavirus 2 infection: a case report and retrospective case reviews

Several cases of myelin oligodendrocyte glycoprotein (MOG) antibody-associated encephalitis have been reported after coronavirus disease 2019 (COVID-19). In this case, the patient presented with focal status epilepticus with impaired awareness, auditory hallucinations, and incoherent speech after CO...

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Detalles Bibliográficos
Autores principales: Lee, Yoonkyung, Ahn, Seon-Jae, Lee, Han-Sang, Kim, Yongmoo, Lee, Seolah, Park, Hyeyoung, Moon, Jangsup, Lee, Sang Kun, Chu, Kon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Encephalitis and Neuroinflammation Society 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295827/
https://www.ncbi.nlm.nih.gov/pubmed/37469677
http://dx.doi.org/10.47936/encephalitis.2022.00129
Descripción
Sumario:Several cases of myelin oligodendrocyte glycoprotein (MOG) antibody-associated encephalitis have been reported after coronavirus disease 2019 (COVID-19). In this case, the patient presented with focal status epilepticus with impaired awareness, auditory hallucinations, and incoherent speech after COVID-19. Brain magnetic resonance imaging revealed no specific findings. Cerebrospinal fluid results showed pleocytosis and MOG antibody testing confirmed anti-MOG antibody with live cell-based fluorescence-activated cell sorting assay. The patient was diagnosed with MOG antibody-associated autoimmune encephalitis and treated with intravenous immunoglobulin, rituximab, and tocilizumab. This case occurred presumably due to auto-antibody production following COVID-19.

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