Myelin oligodendrocyte glycoprotein antibody-associated encephalitis after severe acute respiratory syndrome coronavirus 2 infection: a case report and retrospective case reviews

Several cases of myelin oligodendrocyte glycoprotein (MOG) antibody-associated encephalitis have been reported after coronavirus disease 2019 (COVID-19). In this case, the patient presented with focal status epilepticus with impaired awareness, auditory hallucinations, and incoherent speech after CO...

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Autores principales: Lee, Yoonkyung, Ahn, Seon-Jae, Lee, Han-Sang, Kim, Yongmoo, Lee, Seolah, Park, Hyeyoung, Moon, Jangsup, Lee, Sang Kun, Chu, Kon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Encephalitis and Neuroinflammation Society 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295827/
https://www.ncbi.nlm.nih.gov/pubmed/37469677
http://dx.doi.org/10.47936/encephalitis.2022.00129
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author Lee, Yoonkyung
Ahn, Seon-Jae
Lee, Han-Sang
Kim, Yongmoo
Lee, Seolah
Park, Hyeyoung
Moon, Jangsup
Lee, Sang Kun
Chu, Kon
author_facet Lee, Yoonkyung
Ahn, Seon-Jae
Lee, Han-Sang
Kim, Yongmoo
Lee, Seolah
Park, Hyeyoung
Moon, Jangsup
Lee, Sang Kun
Chu, Kon
author_sort Lee, Yoonkyung
collection PubMed
description Several cases of myelin oligodendrocyte glycoprotein (MOG) antibody-associated encephalitis have been reported after coronavirus disease 2019 (COVID-19). In this case, the patient presented with focal status epilepticus with impaired awareness, auditory hallucinations, and incoherent speech after COVID-19. Brain magnetic resonance imaging revealed no specific findings. Cerebrospinal fluid results showed pleocytosis and MOG antibody testing confirmed anti-MOG antibody with live cell-based fluorescence-activated cell sorting assay. The patient was diagnosed with MOG antibody-associated autoimmune encephalitis and treated with intravenous immunoglobulin, rituximab, and tocilizumab. This case occurred presumably due to auto-antibody production following COVID-19.
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spelling pubmed-102958272023-07-19 Myelin oligodendrocyte glycoprotein antibody-associated encephalitis after severe acute respiratory syndrome coronavirus 2 infection: a case report and retrospective case reviews Lee, Yoonkyung Ahn, Seon-Jae Lee, Han-Sang Kim, Yongmoo Lee, Seolah Park, Hyeyoung Moon, Jangsup Lee, Sang Kun Chu, Kon Encephalitis Case Report Several cases of myelin oligodendrocyte glycoprotein (MOG) antibody-associated encephalitis have been reported after coronavirus disease 2019 (COVID-19). In this case, the patient presented with focal status epilepticus with impaired awareness, auditory hallucinations, and incoherent speech after COVID-19. Brain magnetic resonance imaging revealed no specific findings. Cerebrospinal fluid results showed pleocytosis and MOG antibody testing confirmed anti-MOG antibody with live cell-based fluorescence-activated cell sorting assay. The patient was diagnosed with MOG antibody-associated autoimmune encephalitis and treated with intravenous immunoglobulin, rituximab, and tocilizumab. This case occurred presumably due to auto-antibody production following COVID-19. Korean Encephalitis and Neuroinflammation Society 2023-04 2023-03-28 /pmc/articles/PMC10295827/ /pubmed/37469677 http://dx.doi.org/10.47936/encephalitis.2022.00129 Text en Copyright © 2023 Korean Encephalitis and Neuroinflammation Society https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Yoonkyung
Ahn, Seon-Jae
Lee, Han-Sang
Kim, Yongmoo
Lee, Seolah
Park, Hyeyoung
Moon, Jangsup
Lee, Sang Kun
Chu, Kon
Myelin oligodendrocyte glycoprotein antibody-associated encephalitis after severe acute respiratory syndrome coronavirus 2 infection: a case report and retrospective case reviews
title Myelin oligodendrocyte glycoprotein antibody-associated encephalitis after severe acute respiratory syndrome coronavirus 2 infection: a case report and retrospective case reviews
title_full Myelin oligodendrocyte glycoprotein antibody-associated encephalitis after severe acute respiratory syndrome coronavirus 2 infection: a case report and retrospective case reviews
title_fullStr Myelin oligodendrocyte glycoprotein antibody-associated encephalitis after severe acute respiratory syndrome coronavirus 2 infection: a case report and retrospective case reviews
title_full_unstemmed Myelin oligodendrocyte glycoprotein antibody-associated encephalitis after severe acute respiratory syndrome coronavirus 2 infection: a case report and retrospective case reviews
title_short Myelin oligodendrocyte glycoprotein antibody-associated encephalitis after severe acute respiratory syndrome coronavirus 2 infection: a case report and retrospective case reviews
title_sort myelin oligodendrocyte glycoprotein antibody-associated encephalitis after severe acute respiratory syndrome coronavirus 2 infection: a case report and retrospective case reviews
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295827/
https://www.ncbi.nlm.nih.gov/pubmed/37469677
http://dx.doi.org/10.47936/encephalitis.2022.00129
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