UBL3 Interacts with Alpha-Synuclein in Cells and the Interaction Is Downregulated by the EGFR Pathway Inhibitor Osimertinib

Ubiquitin-like 3 (UBL3) acts as a post-translational modification (PTM) factor and regulates protein sorting into small extracellular vesicles (sEVs). sEVs have been reported as vectors for the pathology propagation of neurodegenerative diseases, such as α-synucleinopathies. Alpha-synuclein (α-syn)...

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Detalles Bibliográficos
Autores principales: Chen, Bin, Hasan, Md. Mahmudul, Zhang, Hengsen, Zhai, Qing, Waliullah, A. S. M., Ping, Yashuang, Zhang, Chi, Oyama, Soho, Mimi, Mst. Afsana, Tomochika, Yuna, Nagashima, Yu, Nakamura, Tomohiko, Kahyo, Tomoaki, Ogawa, Kenji, Kaneda, Daita, Yoshida, Minoru, Setou, Mitsutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295865/
https://www.ncbi.nlm.nih.gov/pubmed/37371780
http://dx.doi.org/10.3390/biomedicines11061685

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