Low-dose interleukin-2 as a novel therapeutic option for refractory paraneoplastic neurologic syndrome: a case of chronic relapsing anti-Ma2/Ta paraneoplastic myeloradiculopathy

Paraneoplastic neurologic syndromes (PNS) caused by anti-Ma2/Ta antibodies have diverse presentations. Myeloradiculopathy is one anti-Ma2/Ta-associated PNS manifestation. We report the case of a patient with chronic relapsing anti-Ma2/Ta paraneoplastic myeloradiculopathy. The patient was successfull...

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Detalles Bibliográficos
Autores principales: Ahn, Seon-Jae, Lee, Han-Sang, Lee, Woo-Jin, Chu, Kon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Encephalitis and Neuroinflammation Society 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295880/
https://www.ncbi.nlm.nih.gov/pubmed/37469846
http://dx.doi.org/10.47936/encephalitis.2021.00038
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author Ahn, Seon-Jae
Lee, Han-Sang
Lee, Woo-Jin
Chu, Kon
author_facet Ahn, Seon-Jae
Lee, Han-Sang
Lee, Woo-Jin
Chu, Kon
author_sort Ahn, Seon-Jae
collection PubMed
description Paraneoplastic neurologic syndromes (PNS) caused by anti-Ma2/Ta antibodies have diverse presentations. Myeloradiculopathy is one anti-Ma2/Ta-associated PNS manifestation. We report the case of a patient with chronic relapsing anti-Ma2/Ta paraneoplastic myeloradiculopathy. The patient was successfully treated with low-dose human recombinant interleukin-2, despite having chronic relapsing symptoms and a refractory response to conventional immunotherapy.
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spelling pubmed-102958802023-07-19 Low-dose interleukin-2 as a novel therapeutic option for refractory paraneoplastic neurologic syndrome: a case of chronic relapsing anti-Ma2/Ta paraneoplastic myeloradiculopathy Ahn, Seon-Jae Lee, Han-Sang Lee, Woo-Jin Chu, Kon Encephalitis Case Report Paraneoplastic neurologic syndromes (PNS) caused by anti-Ma2/Ta antibodies have diverse presentations. Myeloradiculopathy is one anti-Ma2/Ta-associated PNS manifestation. We report the case of a patient with chronic relapsing anti-Ma2/Ta paraneoplastic myeloradiculopathy. The patient was successfully treated with low-dose human recombinant interleukin-2, despite having chronic relapsing symptoms and a refractory response to conventional immunotherapy. Korean Encephalitis and Neuroinflammation Society 2021-07 2021-04-27 /pmc/articles/PMC10295880/ /pubmed/37469846 http://dx.doi.org/10.47936/encephalitis.2021.00038 Text en Copyright © 2021 Korean Encephalitis and Neuroinflammation Society https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ahn, Seon-Jae
Lee, Han-Sang
Lee, Woo-Jin
Chu, Kon
Low-dose interleukin-2 as a novel therapeutic option for refractory paraneoplastic neurologic syndrome: a case of chronic relapsing anti-Ma2/Ta paraneoplastic myeloradiculopathy
title Low-dose interleukin-2 as a novel therapeutic option for refractory paraneoplastic neurologic syndrome: a case of chronic relapsing anti-Ma2/Ta paraneoplastic myeloradiculopathy
title_full Low-dose interleukin-2 as a novel therapeutic option for refractory paraneoplastic neurologic syndrome: a case of chronic relapsing anti-Ma2/Ta paraneoplastic myeloradiculopathy
title_fullStr Low-dose interleukin-2 as a novel therapeutic option for refractory paraneoplastic neurologic syndrome: a case of chronic relapsing anti-Ma2/Ta paraneoplastic myeloradiculopathy
title_full_unstemmed Low-dose interleukin-2 as a novel therapeutic option for refractory paraneoplastic neurologic syndrome: a case of chronic relapsing anti-Ma2/Ta paraneoplastic myeloradiculopathy
title_short Low-dose interleukin-2 as a novel therapeutic option for refractory paraneoplastic neurologic syndrome: a case of chronic relapsing anti-Ma2/Ta paraneoplastic myeloradiculopathy
title_sort low-dose interleukin-2 as a novel therapeutic option for refractory paraneoplastic neurologic syndrome: a case of chronic relapsing anti-ma2/ta paraneoplastic myeloradiculopathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295880/
https://www.ncbi.nlm.nih.gov/pubmed/37469846
http://dx.doi.org/10.47936/encephalitis.2021.00038
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