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Recent Advances in Conjugated Polymer-Based Biosensors for Virus Detection

Nowadays, virus pandemics have become a major burden seriously affecting human health and social and economic development. Thus, the design and fabrication of effective and low-cost techniques for early and accurate virus detection have been given priority for prevention and control of such pandemic...

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Autores principales: Nguyen, Thanh Ngoc, Phung, Viet-Duc, Tran, Vinh Van
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295904/
https://www.ncbi.nlm.nih.gov/pubmed/37366951
http://dx.doi.org/10.3390/bios13060586
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author Nguyen, Thanh Ngoc
Phung, Viet-Duc
Tran, Vinh Van
author_facet Nguyen, Thanh Ngoc
Phung, Viet-Duc
Tran, Vinh Van
author_sort Nguyen, Thanh Ngoc
collection PubMed
description Nowadays, virus pandemics have become a major burden seriously affecting human health and social and economic development. Thus, the design and fabrication of effective and low-cost techniques for early and accurate virus detection have been given priority for prevention and control of such pandemics. Biosensors and bioelectronic devices have been demonstrated as promising technology to resolve the major drawbacks and problems of the current detection methods. Discovering and applying advanced materials have offered opportunities to develop and commercialize biosensor devices for effectively controlling pandemics. Along with various well-known materials such as gold and silver nanoparticles, carbon-based materials, metal oxide-based materials, and graphene, conjugated polymer (CPs) have become one of the most promising candidates for preparation and construction of excellent biosensors with high sensitivity and specificity to different virus analytes owing to their unique π orbital structure and chain conformation alterations, solution processability, and flexibility. Therefore, CP-based biosensors have been regarded as innovative technologies attracting great interest from the community for early diagnosis of COVID-19 as well as other virus pandemics. For providing precious scientific evidence of CP-based biosensor technologies in virus detection, this review aims to give a critical overview of the recent research related to use of CPs in fabrication of virus biosensors. We emphasize structures and interesting characteristics of different CPs and discuss the state-of-the-art applications of CP-based biosensors as well. In addition, different types of biosensors such as optical biosensors, organic thin film transistors (OTFT), and conjugated polymer hydrogels (CPHs) based on CPs are also summarized and presented.
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spelling pubmed-102959042023-06-28 Recent Advances in Conjugated Polymer-Based Biosensors for Virus Detection Nguyen, Thanh Ngoc Phung, Viet-Duc Tran, Vinh Van Biosensors (Basel) Review Nowadays, virus pandemics have become a major burden seriously affecting human health and social and economic development. Thus, the design and fabrication of effective and low-cost techniques for early and accurate virus detection have been given priority for prevention and control of such pandemics. Biosensors and bioelectronic devices have been demonstrated as promising technology to resolve the major drawbacks and problems of the current detection methods. Discovering and applying advanced materials have offered opportunities to develop and commercialize biosensor devices for effectively controlling pandemics. Along with various well-known materials such as gold and silver nanoparticles, carbon-based materials, metal oxide-based materials, and graphene, conjugated polymer (CPs) have become one of the most promising candidates for preparation and construction of excellent biosensors with high sensitivity and specificity to different virus analytes owing to their unique π orbital structure and chain conformation alterations, solution processability, and flexibility. Therefore, CP-based biosensors have been regarded as innovative technologies attracting great interest from the community for early diagnosis of COVID-19 as well as other virus pandemics. For providing precious scientific evidence of CP-based biosensor technologies in virus detection, this review aims to give a critical overview of the recent research related to use of CPs in fabrication of virus biosensors. We emphasize structures and interesting characteristics of different CPs and discuss the state-of-the-art applications of CP-based biosensors as well. In addition, different types of biosensors such as optical biosensors, organic thin film transistors (OTFT), and conjugated polymer hydrogels (CPHs) based on CPs are also summarized and presented. MDPI 2023-05-28 /pmc/articles/PMC10295904/ /pubmed/37366951 http://dx.doi.org/10.3390/bios13060586 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Nguyen, Thanh Ngoc
Phung, Viet-Duc
Tran, Vinh Van
Recent Advances in Conjugated Polymer-Based Biosensors for Virus Detection
title Recent Advances in Conjugated Polymer-Based Biosensors for Virus Detection
title_full Recent Advances in Conjugated Polymer-Based Biosensors for Virus Detection
title_fullStr Recent Advances in Conjugated Polymer-Based Biosensors for Virus Detection
title_full_unstemmed Recent Advances in Conjugated Polymer-Based Biosensors for Virus Detection
title_short Recent Advances in Conjugated Polymer-Based Biosensors for Virus Detection
title_sort recent advances in conjugated polymer-based biosensors for virus detection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295904/
https://www.ncbi.nlm.nih.gov/pubmed/37366951
http://dx.doi.org/10.3390/bios13060586
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