Evolution of magnetic resonance imaging features in cerebral parenchyma from prolonged focal status epilepticus: a case study

It has rarely been documented that permanent alteration of cerebral structures occurs by focal status epilepticus (FSE). We report the case of a 16-year-old boy with FSE in whom serial T1-weighted magnetic resonance volumetry and conventional magnetic resonance imaging were useful for investigating...

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Detalles Bibliográficos
Autores principales: Lim, Sung Chul, Cho, Jung Hee, Shon, Young-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Encephalitis and Neuroinflammation Society 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295910/
https://www.ncbi.nlm.nih.gov/pubmed/37469653
http://dx.doi.org/10.47936/encephalitis.2021.00171
Descripción
Sumario:It has rarely been documented that permanent alteration of cerebral structures occurs by focal status epilepticus (FSE). We report the case of a 16-year-old boy with FSE in whom serial T1-weighted magnetic resonance volumetry and conventional magnetic resonance imaging were useful for investigating an evolving pattern of morphological changes during and after the FSE, including cortical laminar necrosis (CLN), increased T2 signal intensities, and marked regional atrophy on the corresponding areas. Despite cessation of FSE after adequate medication (combination therapy including clobazam of 1 mg/kg/day), further significant cerebral atrophy was detected at the limited regions where discrete CLN had occurred during the FSE.

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