Cargando…
OTUD7B Activates Wnt Signaling Pathway through the Interaction with LEF1
The Wnt signaling pathway plays a critical role in regulating normal cellular processes, including proliferation, differentiation, and apoptosis. Dysregulation of Wnt signaling has been implicated in various human diseases, including cancer. β-catenin and LEF1 are key mediators of Wnt signaling, and...
Autores principales: | Lee, Yuri, Piao, Hai-long, Kim, Jongchan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295924/ https://www.ncbi.nlm.nih.gov/pubmed/37371581 http://dx.doi.org/10.3390/biom13061001 |
Ejemplares similares
-
OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase
por: Kim, Hyo Jin, et al.
Publicado: (2021) -
Oct4 induces EMT through LEF1/β-catenin dependent WNT signaling pathway in hepatocellular carcinoma
por: Sun, Lu, et al.
Publicado: (2017) -
Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation
por: Hao, Yi-Heng, et al.
Publicado: (2019) -
Evolutionary diversification of the canonical Wnt signaling effector TCF/LEF in chordates
por: Torres‐Aguila, Nuria P., et al.
Publicado: (2022) -
AtomNet-Aided OTUD7B Inhibitor Discovery and Validation
por: Chen, Jianfeng, et al.
Publicado: (2023)