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Pharmacological Inhibition of Gasdermin D Suppresses Angiotensin II-Induced Experimental Abdominal Aortic Aneurysms

Background: Gasdermin D, a molecule downstream of the nucleotide-binding oligomerization domain-like receptor family pyrin domain containing inflammasome, forms the membrane pore for the secretion of interleukin (IL)-1β and IL-18, and also mediates pyroptosis. This study was to explore the influence...

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Detalles Bibliográficos
Autores principales: Guo, Jia, Shi, Jinyun, Qin, Min, Wang, Yan, Li, Zhidong, Shoji, Takahiro, Ikezoe, Toru, Ge, Yingbin, Xu, Baohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295961/
https://www.ncbi.nlm.nih.gov/pubmed/37371479
http://dx.doi.org/10.3390/biom13060899