Cargando…

pCR and 2-Year Disease-Free Survival: A Combination of the Two Endpoints as a New Classification for Locally Advanced Rectal Cancer Patients—An Updated Pooled Analysis of Eleven International Randomized Trials

SIMPLE SUMMARY: Locally advanced rectal cancer (LARC) is a heterogeneous disease showing a limited response to neoadjuvant therapies that may be associated with a worse prognosis; therefore, the prediction of long-term outcomes by surrogate endpoints could help with patient stratification from the d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gambacorta, Maria Antonietta, Chiloiro, Giuditta, Masciocchi, Carlotta, Mariani, Silvia, Romano, Angela, Gonnelli, Alessandra, Gerard, Jean-Pierre, Ngan, Samuel, Rödel, Claus, Bujko, Krzysztof, Glynne-Jones, Robert, van Soest, Johan, Dekker, Andre, Damiani, Andrea, Valentini, Vincenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295980/ https://www.ncbi.nlm.nih.gov/pubmed/37370819 http://dx.doi.org/10.3390/cancers15123209

Ejemplares similares

Bayesian network structure for predicting local tumor recurrence in rectal cancer patients treated with neoadjuvant chemoradiation followed by surgery
por: Osong, Biche, et al.
Publicado: (2022)

A process mining approach for clinical guidelines compliance: real-world application in rectal cancer
por: Savino, Mariachiara, et al.
Publicado: (2023)

Delta Radiomics Can Predict Distant Metastasis in Locally Advanced Rectal Cancer: The Challenge to Personalize the Cure
por: Chiloiro, Giuditta, et al.
Publicado: (2020)

A field strength independent MR radiomics model to predict pathological complete response in locally advanced rectal cancer
por: Cusumano, Davide, et al.
Publicado: (2020)

Delta radiomics for rectal cancer response prediction with hybrid 0.35 T magnetic resonance-guided radiotherapy (MRgRT): a hypothesis-generating study for an innovative personalized medicine approach
por: Boldrini, Luca, et al.
Publicado: (2018)

Modern Techniques in Re-Irradiation for Locally Recurrent Rectal Cancer: A Systematic Review
por: Mantello, Giovanna, et al.
Publicado: (2023)

MR-guided radiotherapy in rectal cancer: First clinical experience of an innovative technology
por: Chiloiro, Giuditta, et al.
Publicado: (2019)

Delta Radiomic Analysis of Mesorectum to Predict Treatment Response and Prognosis in Locally Advanced Rectal Cancer
por: Chiloiro, Giuditta, et al.
Publicado: (2023)

Applicability of a pathological complete response magnetic resonance-based radiomics model for locally advanced rectal cancer in intercontinental cohort
por: Boldrini, Luca, et al.
Publicado: (2022)

A Predictive Model of 2yDFS During MR-Guided RT Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Patients
por: Chiloiro, Giuditta, et al.
Publicado: (2022)

Automatic segmentation software in locally advanced rectal cancer: READY (REsearch program in Auto Delineation sYstem)-RECTAL 02: prospective study
por: Gambacorta, Maria A., et al.
Publicado: (2016)

Preoperative intensity-modulated radiotherapy with a simultaneous integrated boost combined with Capecitabine in locally advanced rectal cancer: short-term results of a multicentric study
por: Lupattelli, Marco, et al.
Publicado: (2017)

Fractal-Based Radiomic Approach to Tailor the Chemotherapy Treatment in Rectal Cancer: A Generating Hypothesis Study
por: Di Dio, Carmela, et al.
Publicado: (2021)

Could the conservative approach be considered safe in the treatment of locally advanced rectal cancer in case of a clinical near-complete or complete response? A retrospective analysis
por: Chiloiro, Giuditta, et al.
Publicado: (2021)

Case Report: First in Human Online Adaptive MR Guided SBRT of Peritoneal Carcinomatosis Nodules: A New Therapeutic Approach for the Oligo-Metastatic Patient
por: Boldrini, Luca, et al.
Publicado: (2020)

Beyond geometrical overlap: a Dosimetrical Evaluation of automated volumes Adaptation (DEA) in head and neck replanning
por: Mattiucci, Gian Carlo, et al.
Publicado: (2017)

Mesorectal motion evaluation in rectal cancer MR-guided radiotherapy: an exploratory study to quantify treatment margins
por: Boldrini, Luca, et al.
Publicado: (2023)

Predictive and prognostic value of inflammatory markers in locally advanced rectal cancer (PILLAR) – A multicentric analysis by the Italian Association of Radiotherapy and Clinical Oncology (AIRO) Gastrointestinal Study Group
por: Chiloiro, Giuditta, et al.
Publicado: (2023)

Phase I and II trial on infusional 5-fluorouracil and gefitinib in combination with preoperative radiotherapy in rectal cancer: 10-years median follow-up
por: Gambacorta, Maria Antonietta, et al.
Publicado: (2018)

The Role of Simultaneous Integrated Boost in Locally Advanced Rectal Cancer Patients with Positive Lateral Pelvic Lymph Nodes
por: Meldolesi, Elisa, et al.
Publicado: (2022)

Patients’ Satisfaction by SmileIn(TM) Totems in Radiotherapy: A Two-Year Mono-Institutional Experience
por: Chiloiro, Giuditta, et al.
Publicado: (2021)

Fertility preservation in chemo-radiotherapy for rectal cancer: A combined approach
por: Mariani, S., et al.
Publicado: (2019)

BRIDGE −1 TRIAL: BReak Interval Delayed surgery for Gastrointestinal Extraperitoneal rectal cancer, a multicentric phase III randomized trial
por: Chiloiro, Giuditta, et al.
Publicado: (2022)

Magnetic resonance-guided stereotactic body radiation therapy (MRgSBRT) for oligometastatic patients: a single-center experience
por: Chiloiro, Giuditta, et al.
Publicado: (2023)

Europe forms atom body. Eleven nations to pool funds for research program
Publicado: (1952)

Nomogram for predicting radiation maculopathy in patients treated with Ruthenium-106 plaque brachytherapy for uveal melanoma
por: Tagliaferri, Luca, et al.
Publicado: (2017)

Delta Radiomics Analysis for Local Control Prediction in Pancreatic Cancer Patients Treated Using Magnetic Resonance Guided Radiotherapy
por: Cusumano, Davide, et al.
Publicado: (2021)

International expert consensus statement regarding radiotherapy treatment options for rectal cancer during the COVID 19 pandemic()
por: Marijnen, C.A.M., et al.
Publicado: (2020)

Eleven /
por: Highsmith, Patricia, 1921-1995
Publicado: (1980)

Current practices and perspectives on the integration of contrast agents in MRI-guided radiation therapy clinical practice: A worldwide survey
por: Boldrini, Luca, et al.
Publicado: (2023)

THeragnostic utilities for neoplastic DisEases of the rectum by MRI guided radiotherapy (THUNDER 2) phase II trial: interim safety analysis
por: Chiloiro, Giuditta, et al.
Publicado: (2023)

Time to surgery and pathologic complete response after neoadjuvant chemoradiation in rectal cancer: A population study on 2094 patients
por: Macchia, Gabriella, et al.
Publicado: (2017)

THUNDER 2: THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI guided radiotherapy
por: Chiloiro, Giuditta, et al.
Publicado: (2022)

Prioritization on palliative radiotherapy during the COVID-19 pandemic (and beyond)()
por: Cellini, Francesco, et al.
Publicado: (2020)

Hybrid MRI guided radiotherapy in locally advanced cervical cancer: Case report of an innovative personalized therapeutic approach
por: Boldrini, L., et al.
Publicado: (2019)

On-line adaptive MR guided radiotherapy for locally advanced pancreatic cancer: Clinical and dosimetric considerations
por: Placidi, Lorenzo, et al.
Publicado: (2020)

Possible contribution of IMRT in postoperative radiochemotherapy for rectal cancer: analysis on 1798 patients by prediction model
por: Liu, Wen-Yang, et al.
Publicado: (2016)

Why we should care about gas pockets in online adaptive MRgRT: a dosimetric evaluation
por: Nardini, Matteo, et al.
Publicado: (2023)

Multidisciplinary Tumor Board Smart Virtual Assistant in Locally Advanced Cervical Cancer: A Proof of Concept
por: Macchia, Gabriella, et al.
Publicado: (2022)

Role of neoadjuvant radiochemotherapy for esophageal cancers over pre/peri-operative chemotherapy in the era of COVID-19 and beyond()
por: Cellini, Francesco, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b10d0gsl05fah0f07u35mcaiid