Eradicating Pulmonary Mycobacterium abscessus: The Promise of Dual β-Lactam Therapy

Macrolide resistance has rendered the treatment of Mycobacterium abscessus extremely difficult and is fueling a crisis. Recently, there has been dramatically increased incidence of infections by M abscessus. Select dual β-lactam combinations have shown promising in vitro results. Herein, we present...

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Detalles Bibliográficos
Autores principales: Alahmdi, Bayan, Dousa, Khalid M, Kurz, Sebastian G, Kaufman, Andrew, Bonomo, Robert A, Taimur, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296056/
https://www.ncbi.nlm.nih.gov/pubmed/37383246
http://dx.doi.org/10.1093/ofid/ofad312
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author Alahmdi, Bayan
Dousa, Khalid M
Kurz, Sebastian G
Kaufman, Andrew
Bonomo, Robert A
Taimur, Sarah
author_facet Alahmdi, Bayan
Dousa, Khalid M
Kurz, Sebastian G
Kaufman, Andrew
Bonomo, Robert A
Taimur, Sarah
author_sort Alahmdi, Bayan
collection PubMed
description Macrolide resistance has rendered the treatment of Mycobacterium abscessus extremely difficult and is fueling a crisis. Recently, there has been dramatically increased incidence of infections by M abscessus. Select dual β-lactam combinations have shown promising in vitro results. Herein, we present a patient whose M abscessus infection cured using dual β-lactams as part of multidrug regimen.
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spelling pubmed-102960562023-06-28 Eradicating Pulmonary Mycobacterium abscessus: The Promise of Dual β-Lactam Therapy Alahmdi, Bayan Dousa, Khalid M Kurz, Sebastian G Kaufman, Andrew Bonomo, Robert A Taimur, Sarah Open Forum Infect Dis Brief Report Macrolide resistance has rendered the treatment of Mycobacterium abscessus extremely difficult and is fueling a crisis. Recently, there has been dramatically increased incidence of infections by M abscessus. Select dual β-lactam combinations have shown promising in vitro results. Herein, we present a patient whose M abscessus infection cured using dual β-lactams as part of multidrug regimen. Oxford University Press 2023-06-08 /pmc/articles/PMC10296056/ /pubmed/37383246 http://dx.doi.org/10.1093/ofid/ofad312 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Alahmdi, Bayan
Dousa, Khalid M
Kurz, Sebastian G
Kaufman, Andrew
Bonomo, Robert A
Taimur, Sarah
Eradicating Pulmonary Mycobacterium abscessus: The Promise of Dual β-Lactam Therapy
title Eradicating Pulmonary Mycobacterium abscessus: The Promise of Dual β-Lactam Therapy
title_full Eradicating Pulmonary Mycobacterium abscessus: The Promise of Dual β-Lactam Therapy
title_fullStr Eradicating Pulmonary Mycobacterium abscessus: The Promise of Dual β-Lactam Therapy
title_full_unstemmed Eradicating Pulmonary Mycobacterium abscessus: The Promise of Dual β-Lactam Therapy
title_short Eradicating Pulmonary Mycobacterium abscessus: The Promise of Dual β-Lactam Therapy
title_sort eradicating pulmonary mycobacterium abscessus: the promise of dual β-lactam therapy
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296056/
https://www.ncbi.nlm.nih.gov/pubmed/37383246
http://dx.doi.org/10.1093/ofid/ofad312
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