Successful Treatment of Persistent Symptomatic Coronavirus Disease 19 Infection With Extended-Duration Nirmatrelvir-Ritonavir Among Outpatients With Hematologic Cancer

Persistent symptomatic coronavirus disease 2019 (COVID-19) is a distinct clinical entity among patients with hematologic cancer and/or profound immunosuppression. The optimal medical management is unknown. We describe 2 patients who had symptomatic COVID-19 for almost 6 months and were successfully...

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Autores principales: Liu, Catherine, Yoke, Leah H, Bhattacharyya, Pooja, Cassaday, Ryan D, Cheng, Guang-Shing, Escobar, Zahra Kassamali, Ghiuzeli, Cristina, McCulloch, Denise J, Pergam, Steven A, Roychoudhury, Pavitra, Tverdek, Frank, Schiffer, Joshua T, Ford, Emily S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296060/
https://www.ncbi.nlm.nih.gov/pubmed/37383248
http://dx.doi.org/10.1093/ofid/ofad306
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author Liu, Catherine
Yoke, Leah H
Bhattacharyya, Pooja
Cassaday, Ryan D
Cheng, Guang-Shing
Escobar, Zahra Kassamali
Ghiuzeli, Cristina
McCulloch, Denise J
Pergam, Steven A
Roychoudhury, Pavitra
Tverdek, Frank
Schiffer, Joshua T
Ford, Emily S
author_facet Liu, Catherine
Yoke, Leah H
Bhattacharyya, Pooja
Cassaday, Ryan D
Cheng, Guang-Shing
Escobar, Zahra Kassamali
Ghiuzeli, Cristina
McCulloch, Denise J
Pergam, Steven A
Roychoudhury, Pavitra
Tverdek, Frank
Schiffer, Joshua T
Ford, Emily S
author_sort Liu, Catherine
collection PubMed
description Persistent symptomatic coronavirus disease 2019 (COVID-19) is a distinct clinical entity among patients with hematologic cancer and/or profound immunosuppression. The optimal medical management is unknown. We describe 2 patients who had symptomatic COVID-19 for almost 6 months and were successfully treated in the ambulatory setting with extended courses of nirmatrelvir-ritonavir.
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spelling pubmed-102960602023-06-28 Successful Treatment of Persistent Symptomatic Coronavirus Disease 19 Infection With Extended-Duration Nirmatrelvir-Ritonavir Among Outpatients With Hematologic Cancer Liu, Catherine Yoke, Leah H Bhattacharyya, Pooja Cassaday, Ryan D Cheng, Guang-Shing Escobar, Zahra Kassamali Ghiuzeli, Cristina McCulloch, Denise J Pergam, Steven A Roychoudhury, Pavitra Tverdek, Frank Schiffer, Joshua T Ford, Emily S Open Forum Infect Dis Brief Report Persistent symptomatic coronavirus disease 2019 (COVID-19) is a distinct clinical entity among patients with hematologic cancer and/or profound immunosuppression. The optimal medical management is unknown. We describe 2 patients who had symptomatic COVID-19 for almost 6 months and were successfully treated in the ambulatory setting with extended courses of nirmatrelvir-ritonavir. Oxford University Press 2023-06-06 /pmc/articles/PMC10296060/ /pubmed/37383248 http://dx.doi.org/10.1093/ofid/ofad306 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Liu, Catherine
Yoke, Leah H
Bhattacharyya, Pooja
Cassaday, Ryan D
Cheng, Guang-Shing
Escobar, Zahra Kassamali
Ghiuzeli, Cristina
McCulloch, Denise J
Pergam, Steven A
Roychoudhury, Pavitra
Tverdek, Frank
Schiffer, Joshua T
Ford, Emily S
Successful Treatment of Persistent Symptomatic Coronavirus Disease 19 Infection With Extended-Duration Nirmatrelvir-Ritonavir Among Outpatients With Hematologic Cancer
title Successful Treatment of Persistent Symptomatic Coronavirus Disease 19 Infection With Extended-Duration Nirmatrelvir-Ritonavir Among Outpatients With Hematologic Cancer
title_full Successful Treatment of Persistent Symptomatic Coronavirus Disease 19 Infection With Extended-Duration Nirmatrelvir-Ritonavir Among Outpatients With Hematologic Cancer
title_fullStr Successful Treatment of Persistent Symptomatic Coronavirus Disease 19 Infection With Extended-Duration Nirmatrelvir-Ritonavir Among Outpatients With Hematologic Cancer
title_full_unstemmed Successful Treatment of Persistent Symptomatic Coronavirus Disease 19 Infection With Extended-Duration Nirmatrelvir-Ritonavir Among Outpatients With Hematologic Cancer
title_short Successful Treatment of Persistent Symptomatic Coronavirus Disease 19 Infection With Extended-Duration Nirmatrelvir-Ritonavir Among Outpatients With Hematologic Cancer
title_sort successful treatment of persistent symptomatic coronavirus disease 19 infection with extended-duration nirmatrelvir-ritonavir among outpatients with hematologic cancer
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296060/
https://www.ncbi.nlm.nih.gov/pubmed/37383248
http://dx.doi.org/10.1093/ofid/ofad306
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