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A Local and Abscopal Effect Observed with Liposomal Encapsulation of Intratumorally Injected Oncolytic Adenoviral Therapy

SIMPLE SUMMARY: Oncolytic adenoviruses are genetically engineered to selectively replicate within cancer cells by exploiting their unique characteristics while sparing normal cells. However, adenoviruses generally require the coxsackie and adenovirus receptor (CAR) to enter the cells. This study inv...

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Detalles Bibliográficos
Autores principales: Dong, Tao, Shah, Jaimin R., Phung, Abraham T., Larson, Christopher, Sanchez, Ana B., Aisagbonhi, Omonigho, Blair, Sarah L., Oronsky, Bryan, Trogler, William C., Reid, Tony, Kummel, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296131/
https://www.ncbi.nlm.nih.gov/pubmed/37370769
http://dx.doi.org/10.3390/cancers15123157