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Intravitreal Neuroglobin Mitigates Primate Experimental Glaucomatous Structural Damage in Association with Reduced Optic Nerve Microglial and Complement 3-Astrocyte Activation
Current management of glaucomatous optic neuropathy is limited to intraocular pressure control. Neuroglobin (Ngb) is an endogenous neuroprotectant expressed in neurons and astrocytes. We recently showed that exogenous intravitreal Ngb reduced inflammatory cytokines and microglial activation in a rod...
Autores principales: | Chan, Anita S. Y., Tun, Sai B. B., Lynn, Myoe N., Ho, Candice, Tun, Tin A., Girard, Michaël J. A., Sultana, Rehena, Barathi, Veluchamy A., Aung, Tin, Aihara, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296154/ https://www.ncbi.nlm.nih.gov/pubmed/37371541 http://dx.doi.org/10.3390/biom13060961 |
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