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Diagnosis and Treatment of Sleep Apnea in Children: A Future Perspective Is Needed

Obstructive sleep apnea (OSA) in children is a prevalent, but still, today, underdiagnosed illness, which consists of repetitive episodes of upper airway obstruction during sleep with important repercussions for sleep quality. OSA has relevant consequences in the pediatric population, mainly in the...

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Autores principales: Solano-Pérez, Esther, Coso, Carlota, Castillo-García, María, Romero-Peralta, Sofía, Lopez-Monzoni, Sonia, Laviña, Eduardo, Cano-Pumarega, Irene, Sánchez-de-la-Torre, Manuel, García-Río, Francisco, Mediano, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296156/
https://www.ncbi.nlm.nih.gov/pubmed/37371803
http://dx.doi.org/10.3390/biomedicines11061708
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author Solano-Pérez, Esther
Coso, Carlota
Castillo-García, María
Romero-Peralta, Sofía
Lopez-Monzoni, Sonia
Laviña, Eduardo
Cano-Pumarega, Irene
Sánchez-de-la-Torre, Manuel
García-Río, Francisco
Mediano, Olga
author_facet Solano-Pérez, Esther
Coso, Carlota
Castillo-García, María
Romero-Peralta, Sofía
Lopez-Monzoni, Sonia
Laviña, Eduardo
Cano-Pumarega, Irene
Sánchez-de-la-Torre, Manuel
García-Río, Francisco
Mediano, Olga
author_sort Solano-Pérez, Esther
collection PubMed
description Obstructive sleep apnea (OSA) in children is a prevalent, but still, today, underdiagnosed illness, which consists of repetitive episodes of upper airway obstruction during sleep with important repercussions for sleep quality. OSA has relevant consequences in the pediatric population, mainly in the metabolic, cardiovascular (CV), and neurological spheres. However, contrary to adults, advances in diagnostic and therapeutic management have been scarce in the last few years despite the increasing scientific evidence of the deleterious consequences of pediatric OSA. The problem of underdiagnosis and the lack of response to treatment in some groups make an update to the management of OSA in children necessary. Probably, the heterogeneity of OSA is not well represented by the classical clinical presentation and severity parameters (apnea/hypopnea index (AHI)), and new strategies are required. A specific and consensus definition should be established. Additionally, the role of simplified methods in the diagnosis algorithm should be considered. Finally, the search for new biomarkers for risk stratification is needed in this population. In conclusion, new paradigms based on personalized medicine should be implemented in this population.
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spelling pubmed-102961562023-06-28 Diagnosis and Treatment of Sleep Apnea in Children: A Future Perspective Is Needed Solano-Pérez, Esther Coso, Carlota Castillo-García, María Romero-Peralta, Sofía Lopez-Monzoni, Sonia Laviña, Eduardo Cano-Pumarega, Irene Sánchez-de-la-Torre, Manuel García-Río, Francisco Mediano, Olga Biomedicines Review Obstructive sleep apnea (OSA) in children is a prevalent, but still, today, underdiagnosed illness, which consists of repetitive episodes of upper airway obstruction during sleep with important repercussions for sleep quality. OSA has relevant consequences in the pediatric population, mainly in the metabolic, cardiovascular (CV), and neurological spheres. However, contrary to adults, advances in diagnostic and therapeutic management have been scarce in the last few years despite the increasing scientific evidence of the deleterious consequences of pediatric OSA. The problem of underdiagnosis and the lack of response to treatment in some groups make an update to the management of OSA in children necessary. Probably, the heterogeneity of OSA is not well represented by the classical clinical presentation and severity parameters (apnea/hypopnea index (AHI)), and new strategies are required. A specific and consensus definition should be established. Additionally, the role of simplified methods in the diagnosis algorithm should be considered. Finally, the search for new biomarkers for risk stratification is needed in this population. In conclusion, new paradigms based on personalized medicine should be implemented in this population. MDPI 2023-06-14 /pmc/articles/PMC10296156/ /pubmed/37371803 http://dx.doi.org/10.3390/biomedicines11061708 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Solano-Pérez, Esther
Coso, Carlota
Castillo-García, María
Romero-Peralta, Sofía
Lopez-Monzoni, Sonia
Laviña, Eduardo
Cano-Pumarega, Irene
Sánchez-de-la-Torre, Manuel
García-Río, Francisco
Mediano, Olga
Diagnosis and Treatment of Sleep Apnea in Children: A Future Perspective Is Needed
title Diagnosis and Treatment of Sleep Apnea in Children: A Future Perspective Is Needed
title_full Diagnosis and Treatment of Sleep Apnea in Children: A Future Perspective Is Needed
title_fullStr Diagnosis and Treatment of Sleep Apnea in Children: A Future Perspective Is Needed
title_full_unstemmed Diagnosis and Treatment of Sleep Apnea in Children: A Future Perspective Is Needed
title_short Diagnosis and Treatment of Sleep Apnea in Children: A Future Perspective Is Needed
title_sort diagnosis and treatment of sleep apnea in children: a future perspective is needed
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296156/
https://www.ncbi.nlm.nih.gov/pubmed/37371803
http://dx.doi.org/10.3390/biomedicines11061708
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