Efflux Pump-Binding 4(3-Aminocyclobutyl)Pyrimidin-2-Amines Are Colloidal Aggregators

Efflux pumps are a relevant factor in antimicrobial resistance. In E. coli, the tripartite efflux pump AcrAB-TolC removes a chemically diverse set of antibiotics from the bacterium. Therefore, small molecules interfering with efflux pump function are considered adjuvants for improving antimicrobial...

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Detalles Bibliográficos
Autores principales: Szal, Tania, Chauhan, Shweta Singh, Lewe, Philipp, Rachad, Fatima-Zahra, Madre, Marina, Paunina, Laura, Witt, Susanne, Parthasarathi, Ramakrishnan, Windshügel, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296211/
https://www.ncbi.nlm.nih.gov/pubmed/37371580
http://dx.doi.org/10.3390/biom13061000

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