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LIN28B and Let-7 in Diffuse Midline Glioma: A Review

SIMPLE SUMMARY: Diffuse midline glioma (DMG) is a devastating pediatric brain tumor with urgent unmet need for novel treatment modalities. LIN28B RNA binding protein is overexpressed in DMG and suppresses the let-7 family of microRNAs, which in turn suppress a plethora of oncogenes. In the present r...

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Detalles Bibliográficos
Autores principales:	Knowles, Truman, Huang, Tina, Qi, Jin, An, Shejuan, Burket, Noah, Cooper, Scott, Nazarian, Javad, Saratsis, Amanda M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296230/ https://www.ncbi.nlm.nih.gov/pubmed/37370851 http://dx.doi.org/10.3390/cancers15123241

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