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Acetate-Mediated Odorant Receptor OR51E2 Activation Results in Calcitonin Secretion in Parafollicular C-Cells: A Novel Diagnostic Target of Human Medullary Thyroid Cancer

Medullary thyroid cancer originates from parafollicular C-cells in the thyroid. Despite successful thyroidectomy, localizing remnant cancer cells in patients with elevated calcitonin and carcinoembryonic antigen levels remains a challenge. Extranasal odorant receptors are expressed in cells from non...

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Detalles Bibliográficos
Autores principales: Lee, Hyeon Jeong, Ku, Cheol Ryong, Cho, Arthur, Cho, TaeHo, Lee, ChaeEun, Kang, Chan Woo, Kim, Daham, Cho, Yoon Hee, Koo, JaeHyung, Lee, Eun Jig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296248/
https://www.ncbi.nlm.nih.gov/pubmed/37371783
http://dx.doi.org/10.3390/biomedicines11061688

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