Pharmaceuticals Promoting Premature Termination Codon Readthrough: Progress in Development

Around 11% of all known gene lesions causing human genetic diseases are nonsense mutations that introduce a premature stop codon (PTC) into the protein-coding gene sequence. Drug-induced PTC readthrough is a promising therapeutic strategy for treating hereditary diseases caused by nonsense mutations...

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Detalles Bibliográficos
Autores principales: Li, Shan, Li, Juan, Shi, Wenjing, Nie, Ziyan, Zhang, Shasha, Ma, Fengdie, Hu, Jun, Chen, Jianjun, Li, Peiqiang, Xie, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296333/
https://www.ncbi.nlm.nih.gov/pubmed/37371567
http://dx.doi.org/10.3390/biom13060988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296333/
https://www.ncbi.nlm.nih.gov/pubmed/37371567
http://dx.doi.org/10.3390/biom13060988

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