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Age-Related Effects of Exogenous Melatonin on Anxiety-like Behavior in C57/B6J Mice

The synthesis of melatonin (MLT) physiologically decreases during aging. Treatment with MLT has shown anxiolytic, hypnotic, and analgesic effects, but little is known about possible age-dependent differences in its efficacy. Therefore, we studied the effects of MLT (20 mg/kg, intraperitoneal) on anx...

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Detalles Bibliográficos
Autores principales: Nasini, Sofia, Tidei, Sara, Shkodra, Atea, De Gregorio, Danilo, Cambiaghi, Marco, Comai, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296393/
https://www.ncbi.nlm.nih.gov/pubmed/37371801
http://dx.doi.org/10.3390/biomedicines11061705