c-Myc/microRNA-17-92 Axis Phase-Dependently Regulates PTEN and p21 Expression via ceRNA during Reprogramming to Mouse Pluripotent Stem Cells

Induced pluripotent stem cells (iPSCs) are promising cell sources for regenerative medicine and disease modeling. iPSCs are commonly established by introducing the defined reprogramming factors Oct4, Sox2, Klf4, and c-Myc. However, iPSC reprogramming efficiency remains low. Although recent studies h...

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Detalles Bibliográficos
Autores principales: Ishida, Tomoaki, Ueyama, Tomoe, Ihara, Dai, Harada, Yukihiro, Nakagawa, Sae, Saito, Kaho, Nakao, Shu, Kawamura, Teruhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296502/
https://www.ncbi.nlm.nih.gov/pubmed/37371832
http://dx.doi.org/10.3390/biomedicines11061737

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