The RHOA Mutation G17V Does Not Lead to Increased Migration of Human Malignant T Cells but Is Associated with Matrix Remodelling

SIMPLE SUMMARY: The aim of this study was to understand if the presence of a RHOA-G17V mutation in angioimmunoblastic T-cell lymphoma is responsible for the typical clinical presentation with early dissemination of tumor cells. Overexpression of RHOA-G17V in malignant T cells did not enhance their m...

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Detalles Bibliográficos
Autores principales: Merk-Ahmad, Katrin, Bein, Julia, Scharf, Sonja, Schäfer, Hendrik, Bexte, Tobias, Ullrich, Evelyn, Loth, Andreas G., Flinner, Nadine, Senff, Tina, Schneider, Olga, Hansmann, Martin-Leo, Piel, Matthieu, Häupl, Björn, Oellerich, Thomas, Donnadieu, Emmanuel, Hartmann, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296629/
https://www.ncbi.nlm.nih.gov/pubmed/37370838
http://dx.doi.org/10.3390/cancers15123226

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