Pharmacological Characterization of P626, a Novel Dual Adenosine A(2A)/A(2B) Receptor Antagonist, on Synaptic Plasticity and during an Ischemic-like Insult in CA1 Rat Hippocampus

In recent years, the use of multi-target compounds has become an increasingly pursued strategy to treat complex pathologies, including cerebral ischemia. Adenosine and its receptors (A(1)AR, A(2A)AR, A(2B)AR, A(3)AR) are known to play a crucial role in synaptic transmission either in normoxic or isc...

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Detalles Bibliográficos
Autores principales: Venturini, Martina, Cherchi, Federica, Santalmasi, Clara, Frulloni, Lucia, Dettori, Ilaria, Catarzi, Daniela, Pedata, Felicita, Colotta, Vittoria, Varano, Flavia, Coppi, Elisabetta, Pugliese, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296693/
https://www.ncbi.nlm.nih.gov/pubmed/37371474
http://dx.doi.org/10.3390/biom13060894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296693/
https://www.ncbi.nlm.nih.gov/pubmed/37371474
http://dx.doi.org/10.3390/biom13060894

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