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YES1 Kinase Mediates the Membrane Removal of Rescued F508del-CFTR in Airway Cells by Promoting MAPK Pathway Activation via SHC1

Recent developments in CFTR modulator drugs have had a significant transformational effect on the treatment of individuals with Cystic Fibrosis (CF) who carry the most frequent F508del-CFTR mutation in at least one allele. However, the clinical effects of these revolutionary drugs remain limited by...

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Detalles Bibliográficos
Autores principales:	Barros, Patrícia, Matos, Ana M., Matos, Paulo, Jordan, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296715/ https://www.ncbi.nlm.nih.gov/pubmed/37371529 http://dx.doi.org/10.3390/biom13060949

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