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Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid Signaling

Multiple inositol polyphosphate phosphatase (MINPP1) is an enigmatic enzyme that is responsible for the metabolism of inositol hexakisphosphate (InsP(6)) and inositol 1,3,4,5,6 pentakisphosphate (Ins(1,3,4,5,6)P(5) in mammalian cells, despite being restricted to the confines of the ER. The reason fo...

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Detalles Bibliográficos
Autores principales: Yu, Jia, Leibiger, Barbara, Yang, Shao-Nian, Shears, Stephen B., Leibiger, Ingo B., Berggren, Per-Olof, Barker, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296752/
https://www.ncbi.nlm.nih.gov/pubmed/37371464
http://dx.doi.org/10.3390/biom13060885