A Robust FISH Assay to Detect FGFR2 Translocations in Intrahepatic Cholangiocarcinoma Patients

FGFR fusions retaining the FGFR kinase domain are active kinases that are either overexpressed or constitutively activated throughout diverse cancer types. The presence of FGFR translocations enhances tumor cell proliferation and contributes to significant sensitivity to FGFR kinase inhibitors. FGFR...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Zheng, Hao, Xu, Linyu, You, Si, Shen, Yuanyuan, Han, Yang, Anderson, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296881/
https://www.ncbi.nlm.nih.gov/pubmed/37370984
http://dx.doi.org/10.3390/diagnostics13122088

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