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Evaluation of Anal Sphincter with High Resolution Anorectal Manometry and 3D Reconstruction in Patients with Anorectal Malformation

Background: Patients with anorectal malformation (ARM) need long-term follow-up, in order to evaluate fecal continence; the main predictors of longer-term success are the type of ARM, associated anomalies and sacral integrity. Three-Dimensional High Resolution Anorectal Manometry (3D-HRAM) gives det...

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Autores principales: Caruso, Anna Maria, Bommarito, Denisia, Girgenti, Vincenza, Amato, Glenda, Calabrese, Ugo, Figuccia, Adele, Baldanza, Fabio, Grasso, Francesco, Giglione, Emanuela, Casuccio, Alessandra, Milazzo, Mario Pietro Marcello, Di Pace, Maria Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296972/
https://www.ncbi.nlm.nih.gov/pubmed/37371268
http://dx.doi.org/10.3390/children10061037
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author Caruso, Anna Maria
Bommarito, Denisia
Girgenti, Vincenza
Amato, Glenda
Calabrese, Ugo
Figuccia, Adele
Baldanza, Fabio
Grasso, Francesco
Giglione, Emanuela
Casuccio, Alessandra
Milazzo, Mario Pietro Marcello
Di Pace, Maria Rita
author_facet Caruso, Anna Maria
Bommarito, Denisia
Girgenti, Vincenza
Amato, Glenda
Calabrese, Ugo
Figuccia, Adele
Baldanza, Fabio
Grasso, Francesco
Giglione, Emanuela
Casuccio, Alessandra
Milazzo, Mario Pietro Marcello
Di Pace, Maria Rita
author_sort Caruso, Anna Maria
collection PubMed
description Background: Patients with anorectal malformation (ARM) need long-term follow-up, in order to evaluate fecal continence; the main predictors of longer-term success are the type of ARM, associated anomalies and sacral integrity. Three-Dimensional High Resolution Anorectal Manometry (3D-HRAM) gives detailed information on pressure on the anal complex profile. Our objective was to analyze anal sphincter activity in ARM patients with 3D-HRAM establishing the correlation between manometric and clinical data. Methods: Forty ARM patients were submitted to 3D-HRAM: manometric, anatomical and clinical scores were correlated with each other and with the bowel management response (BM). Results: A positive correlation between all scores and types of ARM was found: in high ARM and in patients with spinal anomalies (regardless to ARM type) lower scores were reported and even after BM they did not achieve good continence. Conclusions: 3D-HRAM gives detailed data on the functional activity of the anal sphincter complex. Our study revealed a correlation between manometric parameters and clinical outcomes, confirming spinal malformations and ARM type as the most important prognostic risk factors for a bad outcome. Specific sphincteric defects can also be explored with manometry, allowing for tailored bowel management strategies.
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spelling pubmed-102969722023-06-28 Evaluation of Anal Sphincter with High Resolution Anorectal Manometry and 3D Reconstruction in Patients with Anorectal Malformation Caruso, Anna Maria Bommarito, Denisia Girgenti, Vincenza Amato, Glenda Calabrese, Ugo Figuccia, Adele Baldanza, Fabio Grasso, Francesco Giglione, Emanuela Casuccio, Alessandra Milazzo, Mario Pietro Marcello Di Pace, Maria Rita Children (Basel) Article Background: Patients with anorectal malformation (ARM) need long-term follow-up, in order to evaluate fecal continence; the main predictors of longer-term success are the type of ARM, associated anomalies and sacral integrity. Three-Dimensional High Resolution Anorectal Manometry (3D-HRAM) gives detailed information on pressure on the anal complex profile. Our objective was to analyze anal sphincter activity in ARM patients with 3D-HRAM establishing the correlation between manometric and clinical data. Methods: Forty ARM patients were submitted to 3D-HRAM: manometric, anatomical and clinical scores were correlated with each other and with the bowel management response (BM). Results: A positive correlation between all scores and types of ARM was found: in high ARM and in patients with spinal anomalies (regardless to ARM type) lower scores were reported and even after BM they did not achieve good continence. Conclusions: 3D-HRAM gives detailed data on the functional activity of the anal sphincter complex. Our study revealed a correlation between manometric parameters and clinical outcomes, confirming spinal malformations and ARM type as the most important prognostic risk factors for a bad outcome. Specific sphincteric defects can also be explored with manometry, allowing for tailored bowel management strategies. MDPI 2023-06-09 /pmc/articles/PMC10296972/ /pubmed/37371268 http://dx.doi.org/10.3390/children10061037 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Caruso, Anna Maria
Bommarito, Denisia
Girgenti, Vincenza
Amato, Glenda
Calabrese, Ugo
Figuccia, Adele
Baldanza, Fabio
Grasso, Francesco
Giglione, Emanuela
Casuccio, Alessandra
Milazzo, Mario Pietro Marcello
Di Pace, Maria Rita
Evaluation of Anal Sphincter with High Resolution Anorectal Manometry and 3D Reconstruction in Patients with Anorectal Malformation
title Evaluation of Anal Sphincter with High Resolution Anorectal Manometry and 3D Reconstruction in Patients with Anorectal Malformation
title_full Evaluation of Anal Sphincter with High Resolution Anorectal Manometry and 3D Reconstruction in Patients with Anorectal Malformation
title_fullStr Evaluation of Anal Sphincter with High Resolution Anorectal Manometry and 3D Reconstruction in Patients with Anorectal Malformation
title_full_unstemmed Evaluation of Anal Sphincter with High Resolution Anorectal Manometry and 3D Reconstruction in Patients with Anorectal Malformation
title_short Evaluation of Anal Sphincter with High Resolution Anorectal Manometry and 3D Reconstruction in Patients with Anorectal Malformation
title_sort evaluation of anal sphincter with high resolution anorectal manometry and 3d reconstruction in patients with anorectal malformation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296972/
https://www.ncbi.nlm.nih.gov/pubmed/37371268
http://dx.doi.org/10.3390/children10061037
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