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DDIT4 Downregulation by siRNA Approach Increases the Activity of Proteins Regulating Fatty Acid Metabolism upon Aspirin Treatment in Human Breast Cancer Cells

Repositioning of aspirin for a more effective breast cancer (BC) treatment requires identification of predictive biomarkers. However, the molecular mechanism underlying the anticancer activity of aspirin remains fully undefined. Cancer cells enhance de novo fatty acid (FA) synthesis and FA oxidation...

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Detalles Bibliográficos
Autores principales: Savukaitytė, Aistė, Bartnykaitė, Agnė, Bekampytė, Justina, Ugenskienė, Rasa, Juozaitytė, Elona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297095/
https://www.ncbi.nlm.nih.gov/pubmed/37367045
http://dx.doi.org/10.3390/cimb45060296