Identification of Small Molecules Affecting the Secretion of Therapeutic Antibodies with the Retention Using Selective Hook (RUSH) System

Unlocking cell secretion capacity is of paramount interest for the pharmaceutical industry focused on biologics. Here, we leveraged retention using a selective hook (RUSH) system for the identification of human osteosarcoma U2OS cell secretion modulators, through automated, high-throughput screening...

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Detalles Bibliográficos
Autores principales: Coulet, Mathilde, Lachkar, Sylvie, Leduc, Marion, Trombe, Marc, Gouveia, Zelia, Perez, Franck, Kepp, Oliver, Kroemer, Guido, Basmaciogullari, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297138/
https://www.ncbi.nlm.nih.gov/pubmed/37371112
http://dx.doi.org/10.3390/cells12121642

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