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RNA Aptamer Targeting of Adam8 in Cancer Growth and Metastasis

SIMPLE SUMMARY: An RNA aptamer targeting the extracellular sheddase domain of Adam8 was isolated and characterized both in vitro and in vivo. In co-cultures of human mesenchymal stem cells with human MDA-MB-231 breast cancer or Hep G2 cell liver cancer cells, the aptamer blocked extracellular Adam8...

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Detalles Bibliográficos
Autores principales:	Mi, Zhiyong, Kuo, Marissa C., Kuo, Paul C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297143/ https://www.ncbi.nlm.nih.gov/pubmed/37370863 http://dx.doi.org/10.3390/cancers15123254

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