MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage

Subarachnoid hemorrhage (SAH) is most commonly seen in patients over 55 years of age and often results in a loss of many productive years. SAH has a high mortality rate, and survivors often suffer from early and secondary brain injuries. Understanding the pathophysiology of the SAH is crucial in ide...

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Detalles Bibliográficos
Autores principales: Segherlou, Zahra Hasanpour, Saldarriaga, Lennon, Azizi, Esaan, Vo, Kim-Anh, Reddy, Ramya, Siyanaki, Mohammad Reza Hosseini, Lucke-Wold, Brandon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297144/
https://www.ncbi.nlm.nih.gov/pubmed/37366865
http://dx.doi.org/10.3390/diseases11020077
Descripción
Sumario:Subarachnoid hemorrhage (SAH) is most commonly seen in patients over 55 years of age and often results in a loss of many productive years. SAH has a high mortality rate, and survivors often suffer from early and secondary brain injuries. Understanding the pathophysiology of the SAH is crucial in identifying potential therapeutic agents. One promising target for the diagnosis and prognosis of SAH is circulating microRNAs, which regulate gene expression and are involved in various physiological and pathological processes. In this review, we discuss the potential of microRNAs as a target for diagnosis, treatment, and prognosis in SAH.

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