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MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is most commonly seen in patients over 55 years of age and often results in a loss of many productive years. SAH has a high mortality rate, and survivors often suffer from early and secondary brain injuries. Understanding the pathophysiology of the SAH is crucial in ide...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297144/ https://www.ncbi.nlm.nih.gov/pubmed/37366865 http://dx.doi.org/10.3390/diseases11020077 |
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author | Segherlou, Zahra Hasanpour Saldarriaga, Lennon Azizi, Esaan Vo, Kim-Anh Reddy, Ramya Siyanaki, Mohammad Reza Hosseini Lucke-Wold, Brandon |
author_facet | Segherlou, Zahra Hasanpour Saldarriaga, Lennon Azizi, Esaan Vo, Kim-Anh Reddy, Ramya Siyanaki, Mohammad Reza Hosseini Lucke-Wold, Brandon |
author_sort | Segherlou, Zahra Hasanpour |
collection | PubMed |
description | Subarachnoid hemorrhage (SAH) is most commonly seen in patients over 55 years of age and often results in a loss of many productive years. SAH has a high mortality rate, and survivors often suffer from early and secondary brain injuries. Understanding the pathophysiology of the SAH is crucial in identifying potential therapeutic agents. One promising target for the diagnosis and prognosis of SAH is circulating microRNAs, which regulate gene expression and are involved in various physiological and pathological processes. In this review, we discuss the potential of microRNAs as a target for diagnosis, treatment, and prognosis in SAH. |
format | Online Article Text |
id | pubmed-10297144 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102971442023-06-28 MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage Segherlou, Zahra Hasanpour Saldarriaga, Lennon Azizi, Esaan Vo, Kim-Anh Reddy, Ramya Siyanaki, Mohammad Reza Hosseini Lucke-Wold, Brandon Diseases Review Subarachnoid hemorrhage (SAH) is most commonly seen in patients over 55 years of age and often results in a loss of many productive years. SAH has a high mortality rate, and survivors often suffer from early and secondary brain injuries. Understanding the pathophysiology of the SAH is crucial in identifying potential therapeutic agents. One promising target for the diagnosis and prognosis of SAH is circulating microRNAs, which regulate gene expression and are involved in various physiological and pathological processes. In this review, we discuss the potential of microRNAs as a target for diagnosis, treatment, and prognosis in SAH. MDPI 2023-05-23 /pmc/articles/PMC10297144/ /pubmed/37366865 http://dx.doi.org/10.3390/diseases11020077 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Segherlou, Zahra Hasanpour Saldarriaga, Lennon Azizi, Esaan Vo, Kim-Anh Reddy, Ramya Siyanaki, Mohammad Reza Hosseini Lucke-Wold, Brandon MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage |
title | MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage |
title_full | MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage |
title_fullStr | MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage |
title_full_unstemmed | MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage |
title_short | MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage |
title_sort | micrornas’ role in diagnosis and treatment of subarachnoid hemorrhage |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297144/ https://www.ncbi.nlm.nih.gov/pubmed/37366865 http://dx.doi.org/10.3390/diseases11020077 |
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