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High-LET-Radiation-Induced Persistent DNA Damage Response Signaling and Gastrointestinal Cancer Development

Ionizing radiation (IR) dose, dose rate, and linear energy transfer (LET) determine cellular DNA damage quality and quantity. High-LET heavy ions are prevalent in the deep space environment and can deposit a much greater fraction of total energy in a shorter distance within a cell, causing extensive...

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Detalles Bibliográficos
Autores principales:	Kumar, Kamendra, Kumar, Santosh, Datta, Kamal, Fornace, Albert J., Suman, Shubhankar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297158/ https://www.ncbi.nlm.nih.gov/pubmed/37366899 http://dx.doi.org/10.3390/curroncol30060416

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