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Multiple Myeloma: Case of a “Moving” Sternal Wire

Multiple myeloma generally occurs in older adults, with the clonal proliferation of plasma cells and accumulation of monoclonal protein resulting in a broad range of clinical manifestations and complications, including hypercalcemia, renal dysfunction, anaemia, and bone destruction (termed CRAB feat...

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Autores principales: Choo, Yun Song, Ooi, Melissa Gaik-Ming, Wang, Shi, Hallinan, James Thomas Patrick Decourcy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297185/
https://www.ncbi.nlm.nih.gov/pubmed/37370977
http://dx.doi.org/10.3390/diagnostics13122082
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author Choo, Yun Song
Ooi, Melissa Gaik-Ming
Wang, Shi
Hallinan, James Thomas Patrick Decourcy
author_facet Choo, Yun Song
Ooi, Melissa Gaik-Ming
Wang, Shi
Hallinan, James Thomas Patrick Decourcy
author_sort Choo, Yun Song
collection PubMed
description Multiple myeloma generally occurs in older adults, with the clonal proliferation of plasma cells and accumulation of monoclonal protein resulting in a broad range of clinical manifestations and complications, including hypercalcemia, renal dysfunction, anaemia, and bone destruction (termed CRAB features). A 64-year-old man with no history of malignancy presented with an enlarging precordial lump occurring three years post-sternotomy for uneventful coronary artery bypass grafting surgery. Initial investigations showed anaemia and impaired renal function. Multimodal imaging performed for further evaluation showcases the radio-pathological features which can be encountered in haematological malignancy. Subsequent percutaneous biopsy confirmed an underlying plasma cell neoplasm, and a diagnosis of multiple myeloma was achieved. The prompt resolution of the lesions upon the initiation of treatment highlights the importance of early diagnosis and treatment.
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spelling pubmed-102971852023-06-28 Multiple Myeloma: Case of a “Moving” Sternal Wire Choo, Yun Song Ooi, Melissa Gaik-Ming Wang, Shi Hallinan, James Thomas Patrick Decourcy Diagnostics (Basel) Interesting Images Multiple myeloma generally occurs in older adults, with the clonal proliferation of plasma cells and accumulation of monoclonal protein resulting in a broad range of clinical manifestations and complications, including hypercalcemia, renal dysfunction, anaemia, and bone destruction (termed CRAB features). A 64-year-old man with no history of malignancy presented with an enlarging precordial lump occurring three years post-sternotomy for uneventful coronary artery bypass grafting surgery. Initial investigations showed anaemia and impaired renal function. Multimodal imaging performed for further evaluation showcases the radio-pathological features which can be encountered in haematological malignancy. Subsequent percutaneous biopsy confirmed an underlying plasma cell neoplasm, and a diagnosis of multiple myeloma was achieved. The prompt resolution of the lesions upon the initiation of treatment highlights the importance of early diagnosis and treatment. MDPI 2023-06-16 /pmc/articles/PMC10297185/ /pubmed/37370977 http://dx.doi.org/10.3390/diagnostics13122082 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Interesting Images
Choo, Yun Song
Ooi, Melissa Gaik-Ming
Wang, Shi
Hallinan, James Thomas Patrick Decourcy
Multiple Myeloma: Case of a “Moving” Sternal Wire
title Multiple Myeloma: Case of a “Moving” Sternal Wire
title_full Multiple Myeloma: Case of a “Moving” Sternal Wire
title_fullStr Multiple Myeloma: Case of a “Moving” Sternal Wire
title_full_unstemmed Multiple Myeloma: Case of a “Moving” Sternal Wire
title_short Multiple Myeloma: Case of a “Moving” Sternal Wire
title_sort multiple myeloma: case of a “moving” sternal wire
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297185/
https://www.ncbi.nlm.nih.gov/pubmed/37370977
http://dx.doi.org/10.3390/diagnostics13122082
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