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Multiple Myeloma: Case of a “Moving” Sternal Wire
Multiple myeloma generally occurs in older adults, with the clonal proliferation of plasma cells and accumulation of monoclonal protein resulting in a broad range of clinical manifestations and complications, including hypercalcemia, renal dysfunction, anaemia, and bone destruction (termed CRAB feat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297185/ https://www.ncbi.nlm.nih.gov/pubmed/37370977 http://dx.doi.org/10.3390/diagnostics13122082 |
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author | Choo, Yun Song Ooi, Melissa Gaik-Ming Wang, Shi Hallinan, James Thomas Patrick Decourcy |
author_facet | Choo, Yun Song Ooi, Melissa Gaik-Ming Wang, Shi Hallinan, James Thomas Patrick Decourcy |
author_sort | Choo, Yun Song |
collection | PubMed |
description | Multiple myeloma generally occurs in older adults, with the clonal proliferation of plasma cells and accumulation of monoclonal protein resulting in a broad range of clinical manifestations and complications, including hypercalcemia, renal dysfunction, anaemia, and bone destruction (termed CRAB features). A 64-year-old man with no history of malignancy presented with an enlarging precordial lump occurring three years post-sternotomy for uneventful coronary artery bypass grafting surgery. Initial investigations showed anaemia and impaired renal function. Multimodal imaging performed for further evaluation showcases the radio-pathological features which can be encountered in haematological malignancy. Subsequent percutaneous biopsy confirmed an underlying plasma cell neoplasm, and a diagnosis of multiple myeloma was achieved. The prompt resolution of the lesions upon the initiation of treatment highlights the importance of early diagnosis and treatment. |
format | Online Article Text |
id | pubmed-10297185 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102971852023-06-28 Multiple Myeloma: Case of a “Moving” Sternal Wire Choo, Yun Song Ooi, Melissa Gaik-Ming Wang, Shi Hallinan, James Thomas Patrick Decourcy Diagnostics (Basel) Interesting Images Multiple myeloma generally occurs in older adults, with the clonal proliferation of plasma cells and accumulation of monoclonal protein resulting in a broad range of clinical manifestations and complications, including hypercalcemia, renal dysfunction, anaemia, and bone destruction (termed CRAB features). A 64-year-old man with no history of malignancy presented with an enlarging precordial lump occurring three years post-sternotomy for uneventful coronary artery bypass grafting surgery. Initial investigations showed anaemia and impaired renal function. Multimodal imaging performed for further evaluation showcases the radio-pathological features which can be encountered in haematological malignancy. Subsequent percutaneous biopsy confirmed an underlying plasma cell neoplasm, and a diagnosis of multiple myeloma was achieved. The prompt resolution of the lesions upon the initiation of treatment highlights the importance of early diagnosis and treatment. MDPI 2023-06-16 /pmc/articles/PMC10297185/ /pubmed/37370977 http://dx.doi.org/10.3390/diagnostics13122082 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Interesting Images Choo, Yun Song Ooi, Melissa Gaik-Ming Wang, Shi Hallinan, James Thomas Patrick Decourcy Multiple Myeloma: Case of a “Moving” Sternal Wire |
title | Multiple Myeloma: Case of a “Moving” Sternal Wire |
title_full | Multiple Myeloma: Case of a “Moving” Sternal Wire |
title_fullStr | Multiple Myeloma: Case of a “Moving” Sternal Wire |
title_full_unstemmed | Multiple Myeloma: Case of a “Moving” Sternal Wire |
title_short | Multiple Myeloma: Case of a “Moving” Sternal Wire |
title_sort | multiple myeloma: case of a “moving” sternal wire |
topic | Interesting Images |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297185/ https://www.ncbi.nlm.nih.gov/pubmed/37370977 http://dx.doi.org/10.3390/diagnostics13122082 |
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