Heme-Induced Macrophage Phenotype Switching and Impaired Endogenous Opioid Homeostasis Correlate with Chronic Widespread Pain in HIV

Chronic widespread pain (CWP) is associated with a high rate of disability and decreased quality of life in people with HIV-1 (PWH). We previously showed that PWH with CWP have increased hemolysis and elevated plasma levels of cell-free heme, which correlate with low endogenous opioid levels in leuk...

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Detalles Bibliográficos
Autores principales: Chatterjee, Tanima, Arora, Itika, Underwood, Lilly B., Lewis, Terry L., Masjoan Juncos, Juan Xavier, Heath, Sonya L., Goodin, Burel R., Aggarwal, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297192/
https://www.ncbi.nlm.nih.gov/pubmed/37371035
http://dx.doi.org/10.3390/cells12121565

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