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Selective Concurrence of the Long Non-Coding RNA MALAT1 and the Polycomb Repressive Complex 2 to Promoter Regions of Active Genes in MCF7 Breast Cancer Cells

In cancer cells, the long non-coding RNA (lncRNA) MALAT1 has arisen as a key partner for the Polycomb Repressive Complex 2 (PRC2), an epigenetic modifier. However, it is unknown whether this partnership occurs genome-wide at the chromatin level, as most of the studies focus on single genes that are...

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Detalles Bibliográficos
Autores principales: Arratia, Felipe, Fierro, Cristopher, Blanco, Alejandro, Fuentes, Sebastian, Nahuelquen, Daniela, Montecino, Martin, Rojas, Adriana, Aguilar, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297253/
https://www.ncbi.nlm.nih.gov/pubmed/37367050
http://dx.doi.org/10.3390/cimb45060301