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The Efficacy of Regeneration Oil and Almond Oil on Split-Thickness Skin Graft Donor Sites: A Single-Blinded Randomized Controlled Trial

Background and Objectives: Essential oils are a complementary treatment and can play an important role in scar care. The aim of this study was to evaluate and compare the efficacy of a new essential oil (regeneration oil) with a control group on scar quality in healed split-thickness skin graft dono...

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Autores principales: Riedler, Karoline, Hecker, Andrzej, Bauer, Birgit, Tax, Christa, Gmainer, Daniel Georg, Pignet, Anna-Lisa, Kamolz, Lars-Peter, Lumenta, David Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297259/
https://www.ncbi.nlm.nih.gov/pubmed/37366928
http://dx.doi.org/10.3390/clinpract13030059
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author Riedler, Karoline
Hecker, Andrzej
Bauer, Birgit
Tax, Christa
Gmainer, Daniel Georg
Pignet, Anna-Lisa
Kamolz, Lars-Peter
Lumenta, David Benjamin
author_facet Riedler, Karoline
Hecker, Andrzej
Bauer, Birgit
Tax, Christa
Gmainer, Daniel Georg
Pignet, Anna-Lisa
Kamolz, Lars-Peter
Lumenta, David Benjamin
author_sort Riedler, Karoline
collection PubMed
description Background and Objectives: Essential oils are a complementary treatment and can play an important role in scar care. The aim of this study was to evaluate and compare the efficacy of a new essential oil (regeneration oil) with a control group on scar quality in healed split-thickness skin graft donor sites. Materials and Methods: A single-center blinded randomized controlled study was performed on 30 patients with healed split-thickness skin graft donor site. The patients were randomly allocated into blended regeneration oil (n = 14) and pure almond oil (n = 16) groups. Application of the assigned oil occurred twice a day for 6 months. Scarring (Patient and Observer Scar Assessment Scale), itching (ITCH Assessment Scale) and scar discoloration (colorimetry) of the donor sites were assessed after 1, 3 and 6 months. Results: We found no statistically significant differences between the groups in any applied parameter. We observed comparable outcomes (scar quality, itchiness, colorit) in healed split-thickness skin graft donor sites for both oils. Conclusions: Regeneration oil and control oil presented comparable results regarding scar quality, itchiness and colorit in healed split-thickness skin graft donor sites after 6 months of application. Both oils are suitable for skin/scar care in split-thickness skin graft donor sites.
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spelling pubmed-102972592023-06-28 The Efficacy of Regeneration Oil and Almond Oil on Split-Thickness Skin Graft Donor Sites: A Single-Blinded Randomized Controlled Trial Riedler, Karoline Hecker, Andrzej Bauer, Birgit Tax, Christa Gmainer, Daniel Georg Pignet, Anna-Lisa Kamolz, Lars-Peter Lumenta, David Benjamin Clin Pract Article Background and Objectives: Essential oils are a complementary treatment and can play an important role in scar care. The aim of this study was to evaluate and compare the efficacy of a new essential oil (regeneration oil) with a control group on scar quality in healed split-thickness skin graft donor sites. Materials and Methods: A single-center blinded randomized controlled study was performed on 30 patients with healed split-thickness skin graft donor site. The patients were randomly allocated into blended regeneration oil (n = 14) and pure almond oil (n = 16) groups. Application of the assigned oil occurred twice a day for 6 months. Scarring (Patient and Observer Scar Assessment Scale), itching (ITCH Assessment Scale) and scar discoloration (colorimetry) of the donor sites were assessed after 1, 3 and 6 months. Results: We found no statistically significant differences between the groups in any applied parameter. We observed comparable outcomes (scar quality, itchiness, colorit) in healed split-thickness skin graft donor sites for both oils. Conclusions: Regeneration oil and control oil presented comparable results regarding scar quality, itchiness and colorit in healed split-thickness skin graft donor sites after 6 months of application. Both oils are suitable for skin/scar care in split-thickness skin graft donor sites. MDPI 2023-05-25 /pmc/articles/PMC10297259/ /pubmed/37366928 http://dx.doi.org/10.3390/clinpract13030059 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Riedler, Karoline
Hecker, Andrzej
Bauer, Birgit
Tax, Christa
Gmainer, Daniel Georg
Pignet, Anna-Lisa
Kamolz, Lars-Peter
Lumenta, David Benjamin
The Efficacy of Regeneration Oil and Almond Oil on Split-Thickness Skin Graft Donor Sites: A Single-Blinded Randomized Controlled Trial
title The Efficacy of Regeneration Oil and Almond Oil on Split-Thickness Skin Graft Donor Sites: A Single-Blinded Randomized Controlled Trial
title_full The Efficacy of Regeneration Oil and Almond Oil on Split-Thickness Skin Graft Donor Sites: A Single-Blinded Randomized Controlled Trial
title_fullStr The Efficacy of Regeneration Oil and Almond Oil on Split-Thickness Skin Graft Donor Sites: A Single-Blinded Randomized Controlled Trial
title_full_unstemmed The Efficacy of Regeneration Oil and Almond Oil on Split-Thickness Skin Graft Donor Sites: A Single-Blinded Randomized Controlled Trial
title_short The Efficacy of Regeneration Oil and Almond Oil on Split-Thickness Skin Graft Donor Sites: A Single-Blinded Randomized Controlled Trial
title_sort efficacy of regeneration oil and almond oil on split-thickness skin graft donor sites: a single-blinded randomized controlled trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297259/
https://www.ncbi.nlm.nih.gov/pubmed/37366928
http://dx.doi.org/10.3390/clinpract13030059
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