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Pharmacogenomic Analyses Implicate B Cell Developmental Status and MKL1 as Determinants of Sensitivity toward Anti-CD20 Monoclonal Antibody Therapy

Monoclonal antibody (mAb) therapy directed against CD20 is an important tool in the treatment of B cell disorders. However, variable patient response and acquired resistance remain important clinical challenges. To identify genetic factors that may influence sensitivity to treatment, the cytotoxic a...

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Detalles Bibliográficos
Autores principales:	Small, George W., Akhtari, Farida S., Green, Adrian J., Havener, Tammy M., Sikes, Michael, Quintanhila, Julia, Gonzalez, Ricardo D., Reif, David M., Motsinger-Reif, Alison A., McLeod, Howard L., Wiltshire, Tim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297299/ https://www.ncbi.nlm.nih.gov/pubmed/37371044 http://dx.doi.org/10.3390/cells12121574

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