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Sentinel Lymph Node Detection in Breast Cancer: An Innovative Technique

(1) Background: Sentinel lymph node biopsy is important in the search for metastases, especially in patients with malignant breast disease. Our study proposed new techniques to prevent complications such as possible postoperative seroma formation, pain or hypoesthesia of the axillary cord and medial...

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Autores principales: Izzo, Paolo, De Intinis, Claudia, Sibio, Simone, Basso, Luigi, Polistena, Andrea, Gabriele, Raimondo, Codacci-Pisanelli, Massimo, Izzo, Luciano, Izzo, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297396/
https://www.ncbi.nlm.nih.gov/pubmed/37370925
http://dx.doi.org/10.3390/diagnostics13122030
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author Izzo, Paolo
De Intinis, Claudia
Sibio, Simone
Basso, Luigi
Polistena, Andrea
Gabriele, Raimondo
Codacci-Pisanelli, Massimo
Izzo, Luciano
Izzo, Sara
author_facet Izzo, Paolo
De Intinis, Claudia
Sibio, Simone
Basso, Luigi
Polistena, Andrea
Gabriele, Raimondo
Codacci-Pisanelli, Massimo
Izzo, Luciano
Izzo, Sara
author_sort Izzo, Paolo
collection PubMed
description (1) Background: Sentinel lymph node biopsy is important in the search for metastases, especially in patients with malignant breast disease. Our study proposed new techniques to prevent complications such as possible postoperative seroma formation, pain or hypoesthesia of the axillary cord and medial arm surface, as well as motor deficits, to avoid disabling outcomes and presents initial data from our experience with the sentinel lymph node biopsy technique. (2) Methods: We mainly used two radioactive tracer detection techniques and a new technique using a radiotracer called Sentimag-magtrace. The positive lymph node was located and removed to perform histologic analysis. In our study, we evaluate 100 patients who underwent breast cancer surgery. (3) Results: We calculated the identification rates of the different methods of sentinel lymph node detection and found that it was 88.9% using radioactive tracers vs. 89.5% using the magnetic tracer technology (Sentimag). (4) Conclusions: Thus, this technique avoids radiation exposure for both patients and health care providers, and can reduce costs and time.
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spelling pubmed-102973962023-06-28 Sentinel Lymph Node Detection in Breast Cancer: An Innovative Technique Izzo, Paolo De Intinis, Claudia Sibio, Simone Basso, Luigi Polistena, Andrea Gabriele, Raimondo Codacci-Pisanelli, Massimo Izzo, Luciano Izzo, Sara Diagnostics (Basel) Article (1) Background: Sentinel lymph node biopsy is important in the search for metastases, especially in patients with malignant breast disease. Our study proposed new techniques to prevent complications such as possible postoperative seroma formation, pain or hypoesthesia of the axillary cord and medial arm surface, as well as motor deficits, to avoid disabling outcomes and presents initial data from our experience with the sentinel lymph node biopsy technique. (2) Methods: We mainly used two radioactive tracer detection techniques and a new technique using a radiotracer called Sentimag-magtrace. The positive lymph node was located and removed to perform histologic analysis. In our study, we evaluate 100 patients who underwent breast cancer surgery. (3) Results: We calculated the identification rates of the different methods of sentinel lymph node detection and found that it was 88.9% using radioactive tracers vs. 89.5% using the magnetic tracer technology (Sentimag). (4) Conclusions: Thus, this technique avoids radiation exposure for both patients and health care providers, and can reduce costs and time. MDPI 2023-06-12 /pmc/articles/PMC10297396/ /pubmed/37370925 http://dx.doi.org/10.3390/diagnostics13122030 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Izzo, Paolo
De Intinis, Claudia
Sibio, Simone
Basso, Luigi
Polistena, Andrea
Gabriele, Raimondo
Codacci-Pisanelli, Massimo
Izzo, Luciano
Izzo, Sara
Sentinel Lymph Node Detection in Breast Cancer: An Innovative Technique
title Sentinel Lymph Node Detection in Breast Cancer: An Innovative Technique
title_full Sentinel Lymph Node Detection in Breast Cancer: An Innovative Technique
title_fullStr Sentinel Lymph Node Detection in Breast Cancer: An Innovative Technique
title_full_unstemmed Sentinel Lymph Node Detection in Breast Cancer: An Innovative Technique
title_short Sentinel Lymph Node Detection in Breast Cancer: An Innovative Technique
title_sort sentinel lymph node detection in breast cancer: an innovative technique
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297396/
https://www.ncbi.nlm.nih.gov/pubmed/37370925
http://dx.doi.org/10.3390/diagnostics13122030
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