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Advances in the Metabolic Mechanism and Functional Characteristics of Equol
Equol is the most potent soy isoflavone metabolite and is produced by specific intestinal microorganisms of mammals. It has promising application possibilities for preventing chronic diseases such as cardiovascular disease, breast cancer, and prostate cancer due to its high antioxidant activity and...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297411/ https://www.ncbi.nlm.nih.gov/pubmed/37372545 http://dx.doi.org/10.3390/foods12122334 |
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author | Gong, Yining Lv, Jiaping Pang, Xiaoyang Zhang, Shuwen Zhang, Guofang Liu, Libo Wang, Yunna Li, Chun |
author_facet | Gong, Yining Lv, Jiaping Pang, Xiaoyang Zhang, Shuwen Zhang, Guofang Liu, Libo Wang, Yunna Li, Chun |
author_sort | Gong, Yining |
collection | PubMed |
description | Equol is the most potent soy isoflavone metabolite and is produced by specific intestinal microorganisms of mammals. It has promising application possibilities for preventing chronic diseases such as cardiovascular disease, breast cancer, and prostate cancer due to its high antioxidant activity and hormone-like activity. Thus, it is of great significance to systematically study the efficient preparation method of equol and its functional activity. This paper elaborates on the metabolic mechanism of equol in humans; focuses on the biological characteristics, synthesis methods, and the currently isolated equol-producing bacteria; and looks forward to its future development and application direction, aiming to provide guidance for the application and promotion of equol in the field of food and health products. |
format | Online Article Text |
id | pubmed-10297411 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102974112023-06-28 Advances in the Metabolic Mechanism and Functional Characteristics of Equol Gong, Yining Lv, Jiaping Pang, Xiaoyang Zhang, Shuwen Zhang, Guofang Liu, Libo Wang, Yunna Li, Chun Foods Review Equol is the most potent soy isoflavone metabolite and is produced by specific intestinal microorganisms of mammals. It has promising application possibilities for preventing chronic diseases such as cardiovascular disease, breast cancer, and prostate cancer due to its high antioxidant activity and hormone-like activity. Thus, it is of great significance to systematically study the efficient preparation method of equol and its functional activity. This paper elaborates on the metabolic mechanism of equol in humans; focuses on the biological characteristics, synthesis methods, and the currently isolated equol-producing bacteria; and looks forward to its future development and application direction, aiming to provide guidance for the application and promotion of equol in the field of food and health products. MDPI 2023-06-10 /pmc/articles/PMC10297411/ /pubmed/37372545 http://dx.doi.org/10.3390/foods12122334 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Gong, Yining Lv, Jiaping Pang, Xiaoyang Zhang, Shuwen Zhang, Guofang Liu, Libo Wang, Yunna Li, Chun Advances in the Metabolic Mechanism and Functional Characteristics of Equol |
title | Advances in the Metabolic Mechanism and Functional Characteristics of Equol |
title_full | Advances in the Metabolic Mechanism and Functional Characteristics of Equol |
title_fullStr | Advances in the Metabolic Mechanism and Functional Characteristics of Equol |
title_full_unstemmed | Advances in the Metabolic Mechanism and Functional Characteristics of Equol |
title_short | Advances in the Metabolic Mechanism and Functional Characteristics of Equol |
title_sort | advances in the metabolic mechanism and functional characteristics of equol |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297411/ https://www.ncbi.nlm.nih.gov/pubmed/37372545 http://dx.doi.org/10.3390/foods12122334 |
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