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Advances in the Metabolic Mechanism and Functional Characteristics of Equol

Equol is the most potent soy isoflavone metabolite and is produced by specific intestinal microorganisms of mammals. It has promising application possibilities for preventing chronic diseases such as cardiovascular disease, breast cancer, and prostate cancer due to its high antioxidant activity and...

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Detalles Bibliográficos
Autores principales: Gong, Yining, Lv, Jiaping, Pang, Xiaoyang, Zhang, Shuwen, Zhang, Guofang, Liu, Libo, Wang, Yunna, Li, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297411/
https://www.ncbi.nlm.nih.gov/pubmed/37372545
http://dx.doi.org/10.3390/foods12122334
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author Gong, Yining
Lv, Jiaping
Pang, Xiaoyang
Zhang, Shuwen
Zhang, Guofang
Liu, Libo
Wang, Yunna
Li, Chun
author_facet Gong, Yining
Lv, Jiaping
Pang, Xiaoyang
Zhang, Shuwen
Zhang, Guofang
Liu, Libo
Wang, Yunna
Li, Chun
author_sort Gong, Yining
collection PubMed
description Equol is the most potent soy isoflavone metabolite and is produced by specific intestinal microorganisms of mammals. It has promising application possibilities for preventing chronic diseases such as cardiovascular disease, breast cancer, and prostate cancer due to its high antioxidant activity and hormone-like activity. Thus, it is of great significance to systematically study the efficient preparation method of equol and its functional activity. This paper elaborates on the metabolic mechanism of equol in humans; focuses on the biological characteristics, synthesis methods, and the currently isolated equol-producing bacteria; and looks forward to its future development and application direction, aiming to provide guidance for the application and promotion of equol in the field of food and health products.
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spelling pubmed-102974112023-06-28 Advances in the Metabolic Mechanism and Functional Characteristics of Equol Gong, Yining Lv, Jiaping Pang, Xiaoyang Zhang, Shuwen Zhang, Guofang Liu, Libo Wang, Yunna Li, Chun Foods Review Equol is the most potent soy isoflavone metabolite and is produced by specific intestinal microorganisms of mammals. It has promising application possibilities for preventing chronic diseases such as cardiovascular disease, breast cancer, and prostate cancer due to its high antioxidant activity and hormone-like activity. Thus, it is of great significance to systematically study the efficient preparation method of equol and its functional activity. This paper elaborates on the metabolic mechanism of equol in humans; focuses on the biological characteristics, synthesis methods, and the currently isolated equol-producing bacteria; and looks forward to its future development and application direction, aiming to provide guidance for the application and promotion of equol in the field of food and health products. MDPI 2023-06-10 /pmc/articles/PMC10297411/ /pubmed/37372545 http://dx.doi.org/10.3390/foods12122334 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gong, Yining
Lv, Jiaping
Pang, Xiaoyang
Zhang, Shuwen
Zhang, Guofang
Liu, Libo
Wang, Yunna
Li, Chun
Advances in the Metabolic Mechanism and Functional Characteristics of Equol
title Advances in the Metabolic Mechanism and Functional Characteristics of Equol
title_full Advances in the Metabolic Mechanism and Functional Characteristics of Equol
title_fullStr Advances in the Metabolic Mechanism and Functional Characteristics of Equol
title_full_unstemmed Advances in the Metabolic Mechanism and Functional Characteristics of Equol
title_short Advances in the Metabolic Mechanism and Functional Characteristics of Equol
title_sort advances in the metabolic mechanism and functional characteristics of equol
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297411/
https://www.ncbi.nlm.nih.gov/pubmed/37372545
http://dx.doi.org/10.3390/foods12122334
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