Cargando…

The Biologist’s Guide to the Glucocorticoid Receptor’s Structure

The glucocorticoid receptor α (GRα) is a member of the nuclear receptor superfamily and functions as a glucocorticoid (GC)-responsive transcription factor. GR can halt inflammation and kill off cancer cells, thus explaining the widespread use of glucocorticoids in the clinic. However, side effects a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deploey, Nick, Van Moortel, Laura, Rogatsky, Inez, Peelman, Frank, De Bosscher, Karolien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297449/ https://www.ncbi.nlm.nih.gov/pubmed/37371105 http://dx.doi.org/10.3390/cells12121636

Ejemplares similares

Improved Glucocorticoid Receptor Ligands: Fantastic Beasts, but How to Find Them?
por: Van Moortel, Laura, et al.
Publicado: (2020)

Endothelial Response to Glucocorticoids in Inflammatory Diseases
por: Zielińska, Karolina A., et al.
Publicado: (2016)

Deep mutational scanning of proteins in mammalian cells
por: Maes, Stefanie, et al.
Publicado: (2023)

How the glucocorticoid receptor contributes to platinum-based therapy resistance in solid cancer
por: Clarisse, Dorien, et al.
Publicado: (2021)

Effect of combining glucocorticoids with Compound A on glucocorticoid receptor responsiveness in lymphoid malignancies
por: Clarisse, Dorien, et al.
Publicado: (2018)

Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages
por: Chinenov, Yurii, et al.
Publicado: (2014)

Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies
por: Clarisse, Dorien, et al.
Publicado: (2017)

Compound A influences gene regulation of the Dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment
por: Desmet, S. J., et al.
Publicado: (2017)

Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells
por: Clarisse, Dorien, et al.
Publicado: (2023)

Whither structural biologists?
por: Kleywegt, Gerard J., et al.
Publicado: (2022)

ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation
por: Van Wyngene, Lise, et al.
Publicado: (2021)

TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity
por: Mori, Raffaele, et al.
Publicado: (2017)

The Forest of Biologists – for biologists, for biology
por: Moulton, O. Claire, et al.
Publicado: (2023)

The Forest of Biologists – for biologists, for biology
por: Claire Moulton, O., et al.
Publicado: (2023)

The AlphaFold Database of Protein Structures: A Biologist’s Guide
por: David, Alessia, et al.
Publicado: (2022)

Carl Woese: A structural biologist’s perspective
por: Moore, Peter B
Publicado: (2014)

Differential Cytokine Profiles upon Comparing Selective versus Classic Glucocorticoid Receptor Modulation in Human Peripheral Blood Mononuclear Cells and Inferior Turbinate Tissue
por: Beck, Ilse M., et al.
Publicado: (2015)

A screening assay for Selective Dimerizing Glucocorticoid Receptor Agonists and Modulators (SEDIGRAM) that are effective against acute inflammation
por: Souffriau, Jolien, et al.
Publicado: (2018)

Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor
por: Petta, Ioanna, et al.
Publicado: (2017)

A biologist’s guide to Bayesian phylogenetic analysis
por: Nascimento, Fabrícia F., et al.
Publicado: (2017)

Physical Science for Biologists
por: Giebisch, Gerhard
Publicado: (1973)

Freud: biologist of the mind
por: Porter, Roy
Publicado: (1980)

Gene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages
por: Sacta, Maria A, et al.
Publicado: (2018)

A guide to (13)C metabolic flux analysis for the cancer biologist
por: Antoniewicz, Maciek R.
Publicado: (2018)

Deep learning – promises for 3D nuclear imaging: a guide for biologists
por: Mougeot, Guillaume, et al.
Publicado: (2022)

Interactive visualization tools for the structural biologist
por: Porebski, Benjamin T., et al.
Publicado: (2013)

Crystal Structure analysis for chemists and biologists
por: Glusker, Jenny P.
Publicado: (1994)

A biologist's guide to mathematical modeling in ecology and evolution /
por: Otto, Sarah P., 1967-
Publicado: (2007)

OR26-6 | LBMON298 The Role Of Nuclear Receptor Coregulator Grip1 In Homeostatic Programming Of Macrophages
por: Dacic, Marija, et al.
Publicado: (2022)

A Modern Algebra for Biologists
por: White, Colin
Publicado: (1964)

Ascaris, The Biologist's Story of Life
por: Burr, H. S.
Publicado: (1938)

Training Experimental Biologists in Bioinformatics
por: Fernandes, Pedro, et al.
Publicado: (2012)

Statistics for biologists
por: Campbell, R. C. (Richard Colin)
Publicado: (1974)

The dialectical biologist /
por: Levins, Richard

Autoradiography for biologists
por: Gahan, P B
Publicado: (1972)

W. Zacheus Cande: Evolutionary biologist in cell biologist's clothing
por: Williams, Ruth
Publicado: (2007)

A Cell Biologist’s Field Guide to Aurora Kinase Inhibitors
por: de Groot, Christian O., et al.
Publicado: (2015)

Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1
por: De Bosscher, Karolien, et al.
Publicado: (2013)

Harry Potter and the structural biologist's (Key)stone
por: Devos, Damien, et al.
Publicado: (2006)

A biologist’s guide to planning and performing quantitative bioimaging experiments
por: Senft, Rebecca A., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_eg66ebq99cfvc7jqd3pcecqc3l