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Repurposing of the Drug Tezosentan for Cancer Therapy

Tezosentan is a vasodilator drug that was originally developed to treat pulmonary arterial hypertension. It acts by inhibiting endothelin (ET) receptors, which are overexpressed in many types of cancer cells. Endothelin-1 (ET1) is a substance produced by the body that causes blood vessels to narrow....

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Detalles Bibliográficos
Autores principales: Ribeiro, Eduarda, Vale, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297528/
https://www.ncbi.nlm.nih.gov/pubmed/37367074
http://dx.doi.org/10.3390/cimb45060325

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