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Neurologic Complications of Cancer Immunotherapy

Immunotherapy has revolutionized cancer treatment over the past decade. As it is increasingly introduced into routine clinical practice, immune-related complications have become more frequent. Accurate diagnosis and treatment are essential, with the goal of reduced patient morbidity. This review aim...

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Detalles Bibliográficos
Autores principales: Alsalem, Aseel N., Scarffe, Leslie A., Briemberg, Hannah R., Aaroe, Ashley E., Harrison, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297570/
https://www.ncbi.nlm.nih.gov/pubmed/37366923
http://dx.doi.org/10.3390/curroncol30060440
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author Alsalem, Aseel N.
Scarffe, Leslie A.
Briemberg, Hannah R.
Aaroe, Ashley E.
Harrison, Rebecca A.
author_facet Alsalem, Aseel N.
Scarffe, Leslie A.
Briemberg, Hannah R.
Aaroe, Ashley E.
Harrison, Rebecca A.
author_sort Alsalem, Aseel N.
collection PubMed
description Immunotherapy has revolutionized cancer treatment over the past decade. As it is increasingly introduced into routine clinical practice, immune-related complications have become more frequent. Accurate diagnosis and treatment are essential, with the goal of reduced patient morbidity. This review aims to discuss the various clinical manifestations, diagnosis, treatments, and prognosis of neurologic complications associated with the use of immune checkpoint inhibitors, adoptive T-cell therapies, and T-cell redirecting therapies. We also outline a suggested clinical approach related to the clinical use of these agents.
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spelling pubmed-102975702023-06-28 Neurologic Complications of Cancer Immunotherapy Alsalem, Aseel N. Scarffe, Leslie A. Briemberg, Hannah R. Aaroe, Ashley E. Harrison, Rebecca A. Curr Oncol Review Immunotherapy has revolutionized cancer treatment over the past decade. As it is increasingly introduced into routine clinical practice, immune-related complications have become more frequent. Accurate diagnosis and treatment are essential, with the goal of reduced patient morbidity. This review aims to discuss the various clinical manifestations, diagnosis, treatments, and prognosis of neurologic complications associated with the use of immune checkpoint inhibitors, adoptive T-cell therapies, and T-cell redirecting therapies. We also outline a suggested clinical approach related to the clinical use of these agents. MDPI 2023-06-19 /pmc/articles/PMC10297570/ /pubmed/37366923 http://dx.doi.org/10.3390/curroncol30060440 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Alsalem, Aseel N.
Scarffe, Leslie A.
Briemberg, Hannah R.
Aaroe, Ashley E.
Harrison, Rebecca A.
Neurologic Complications of Cancer Immunotherapy
title Neurologic Complications of Cancer Immunotherapy
title_full Neurologic Complications of Cancer Immunotherapy
title_fullStr Neurologic Complications of Cancer Immunotherapy
title_full_unstemmed Neurologic Complications of Cancer Immunotherapy
title_short Neurologic Complications of Cancer Immunotherapy
title_sort neurologic complications of cancer immunotherapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297570/
https://www.ncbi.nlm.nih.gov/pubmed/37366923
http://dx.doi.org/10.3390/curroncol30060440
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