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Neurologic Complications of Cancer Immunotherapy
Immunotherapy has revolutionized cancer treatment over the past decade. As it is increasingly introduced into routine clinical practice, immune-related complications have become more frequent. Accurate diagnosis and treatment are essential, with the goal of reduced patient morbidity. This review aim...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297570/ https://www.ncbi.nlm.nih.gov/pubmed/37366923 http://dx.doi.org/10.3390/curroncol30060440 |
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author | Alsalem, Aseel N. Scarffe, Leslie A. Briemberg, Hannah R. Aaroe, Ashley E. Harrison, Rebecca A. |
author_facet | Alsalem, Aseel N. Scarffe, Leslie A. Briemberg, Hannah R. Aaroe, Ashley E. Harrison, Rebecca A. |
author_sort | Alsalem, Aseel N. |
collection | PubMed |
description | Immunotherapy has revolutionized cancer treatment over the past decade. As it is increasingly introduced into routine clinical practice, immune-related complications have become more frequent. Accurate diagnosis and treatment are essential, with the goal of reduced patient morbidity. This review aims to discuss the various clinical manifestations, diagnosis, treatments, and prognosis of neurologic complications associated with the use of immune checkpoint inhibitors, adoptive T-cell therapies, and T-cell redirecting therapies. We also outline a suggested clinical approach related to the clinical use of these agents. |
format | Online Article Text |
id | pubmed-10297570 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102975702023-06-28 Neurologic Complications of Cancer Immunotherapy Alsalem, Aseel N. Scarffe, Leslie A. Briemberg, Hannah R. Aaroe, Ashley E. Harrison, Rebecca A. Curr Oncol Review Immunotherapy has revolutionized cancer treatment over the past decade. As it is increasingly introduced into routine clinical practice, immune-related complications have become more frequent. Accurate diagnosis and treatment are essential, with the goal of reduced patient morbidity. This review aims to discuss the various clinical manifestations, diagnosis, treatments, and prognosis of neurologic complications associated with the use of immune checkpoint inhibitors, adoptive T-cell therapies, and T-cell redirecting therapies. We also outline a suggested clinical approach related to the clinical use of these agents. MDPI 2023-06-19 /pmc/articles/PMC10297570/ /pubmed/37366923 http://dx.doi.org/10.3390/curroncol30060440 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Alsalem, Aseel N. Scarffe, Leslie A. Briemberg, Hannah R. Aaroe, Ashley E. Harrison, Rebecca A. Neurologic Complications of Cancer Immunotherapy |
title | Neurologic Complications of Cancer Immunotherapy |
title_full | Neurologic Complications of Cancer Immunotherapy |
title_fullStr | Neurologic Complications of Cancer Immunotherapy |
title_full_unstemmed | Neurologic Complications of Cancer Immunotherapy |
title_short | Neurologic Complications of Cancer Immunotherapy |
title_sort | neurologic complications of cancer immunotherapy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297570/ https://www.ncbi.nlm.nih.gov/pubmed/37366923 http://dx.doi.org/10.3390/curroncol30060440 |
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