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Phenolic Profiles, Antioxidant, and Hypoglycemic Activities of Ribes meyeri Fruits

Ribes meyeri is a Ribes genus in the Saxifragaceae family, which is used as both medicine and food. However, the active components and biological activities of R. meyeri fruits are still unknown. In this paper, the phenolic components and their antioxidant and hypoglycemic activities of R. meyeri fr...

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Detalles Bibliográficos
Autores principales: Zhang, Le, Wang, Qiang, Zhao, Yayun, Ge, Juan, He, Dajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297579/
https://www.ncbi.nlm.nih.gov/pubmed/37372617
http://dx.doi.org/10.3390/foods12122406
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author Zhang, Le
Wang, Qiang
Zhao, Yayun
Ge, Juan
He, Dajun
author_facet Zhang, Le
Wang, Qiang
Zhao, Yayun
Ge, Juan
He, Dajun
author_sort Zhang, Le
collection PubMed
description Ribes meyeri is a Ribes genus in the Saxifragaceae family, which is used as both medicine and food. However, the active components and biological activities of R. meyeri fruits are still unknown. In this paper, the phenolic components and their antioxidant and hypoglycemic activities of R. meyeri fruits were studied. Firstly, a total of 42 phenolic components of R. meyeri fruits, including 26 anthocyanins, 9 flavonoids, and 7 phenolic acids, were tentatively identified using HPLC-QTOF-MS/MS, and the main four anthocyanins were quantified using UPLC-MS/MS. The result indicated that cyanidin-3-O-rutinoside is the main anthocyanin in the R. meyeri fruits. The anthocyanin fraction of R. meyeri fruits exhibited significant inhibitory activity on α-amylase and α-glucosidase. The anthocyanin fraction from R. meyeri fruits significantly increased the glucose uptake of 3T3-L1 adipocytes. This is the first study of a qualitative and quantitative analysis of the phenolics of R. meyeri fruits.
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spelling pubmed-102975792023-06-28 Phenolic Profiles, Antioxidant, and Hypoglycemic Activities of Ribes meyeri Fruits Zhang, Le Wang, Qiang Zhao, Yayun Ge, Juan He, Dajun Foods Article Ribes meyeri is a Ribes genus in the Saxifragaceae family, which is used as both medicine and food. However, the active components and biological activities of R. meyeri fruits are still unknown. In this paper, the phenolic components and their antioxidant and hypoglycemic activities of R. meyeri fruits were studied. Firstly, a total of 42 phenolic components of R. meyeri fruits, including 26 anthocyanins, 9 flavonoids, and 7 phenolic acids, were tentatively identified using HPLC-QTOF-MS/MS, and the main four anthocyanins were quantified using UPLC-MS/MS. The result indicated that cyanidin-3-O-rutinoside is the main anthocyanin in the R. meyeri fruits. The anthocyanin fraction of R. meyeri fruits exhibited significant inhibitory activity on α-amylase and α-glucosidase. The anthocyanin fraction from R. meyeri fruits significantly increased the glucose uptake of 3T3-L1 adipocytes. This is the first study of a qualitative and quantitative analysis of the phenolics of R. meyeri fruits. MDPI 2023-06-18 /pmc/articles/PMC10297579/ /pubmed/37372617 http://dx.doi.org/10.3390/foods12122406 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Le
Wang, Qiang
Zhao, Yayun
Ge, Juan
He, Dajun
Phenolic Profiles, Antioxidant, and Hypoglycemic Activities of Ribes meyeri Fruits
title Phenolic Profiles, Antioxidant, and Hypoglycemic Activities of Ribes meyeri Fruits
title_full Phenolic Profiles, Antioxidant, and Hypoglycemic Activities of Ribes meyeri Fruits
title_fullStr Phenolic Profiles, Antioxidant, and Hypoglycemic Activities of Ribes meyeri Fruits
title_full_unstemmed Phenolic Profiles, Antioxidant, and Hypoglycemic Activities of Ribes meyeri Fruits
title_short Phenolic Profiles, Antioxidant, and Hypoglycemic Activities of Ribes meyeri Fruits
title_sort phenolic profiles, antioxidant, and hypoglycemic activities of ribes meyeri fruits
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297579/
https://www.ncbi.nlm.nih.gov/pubmed/37372617
http://dx.doi.org/10.3390/foods12122406
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