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Ferroptosis-Mediated Cell Death Induced by NCX4040, The Non-Steroidal Nitric Oxide Donor, in Human Colorectal Cancer Cells: Implications in Therapy

Our recent studies show that the treatment of human ovarian tumor cells with NCX4040 results in significant depletions of cellular glutathione, the formation of reactive oxygen/nitrogen species and cell death. NCX4040 is also cytotoxic to several human colorectal cancer (CRC) cells in vitro and in v...

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Detalles Bibliográficos
Autores principales:	Sinha, Birandra K., Bortner, Carl D., Jarmusch, Alan K., Tokar, Erik J., Murphy, Carri, Wu, Xian, Winter, Heather, Cannon, Ronald E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297642/ https://www.ncbi.nlm.nih.gov/pubmed/37371096 http://dx.doi.org/10.3390/cells12121626

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