Cargando…

Incorporation of Resveratrol in Polymeric Nanogel for Improvement of Its Protective Effects on Cellular and Microsomal Oxidative Stress Models

Nanogels are attractive drug delivery systems that provide high loading capacity for drug molecules, improve their stability, and increase cellular uptake. Natural antioxidants, especially polyphenols such as resveratrol, are distinguished by low aqueous solubility, which hinders therapeutic activit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Radeva, Lyubomira, Stefanova, Denitsa, Yordanov, Yordan, Kamenova, Katya, Petrov, Petar D., Marinova, Maya K., Simeonov, Svilen P., Kondeva-Burdina, Magdalena, Tzankova, Virginia, Yoncheva, Krassimira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297669/ https://www.ncbi.nlm.nih.gov/pubmed/37367121 http://dx.doi.org/10.3390/gels9060450

Ejemplares similares

Functional Nanogel from Natural Substances for Delivery of Doxorubicin †
por: Kamenova, Katya, et al.
Publicado: (2022)

Double-Loaded Doxorubicin/Resveratrol Polymeric Micelles Providing Low Toxicity on Cardiac Cells and Enhanced Cytotoxicity on Lymphoma Cells
por: Radeva, Lyubomira, et al.
Publicado: (2023)

Copolymeric Micelles of Poly(ε-caprolactone) and Poly(methacrylic acid) as Carriers for the Oral Delivery of Resveratrol
por: Kamenova, Katya, et al.
Publicado: (2023)

Formulation of Nanomicelles Loaded with Cannabidiol as a Platform for Neuroprotective Therapy
por: Yordanov, Yordan, et al.
Publicado: (2022)

Synthesis, DFT Study, and In Vitro Evaluation of Antioxidant Properties and Cytotoxic and Cytoprotective Effects of New Hydrazones on SH-SY5Y Neuroblastoma Cell Lines
por: Tzankova, Diana, et al.
Publicado: (2023)

Study on the Neuroprotective, Radical-Scavenging and MAO-B Inhibiting Properties of New Benzimidazole Arylhydrazones as Potential Multi-Target Drugs for the Treatment of Parkinson’s Disease
por: Anastassova, Neda, et al.
Publicado: (2022)

New Indole-3-Propionic Acid and 5-Methoxy-Indole Carboxylic Acid Derived Hydrazone Hybrids as Multifunctional Neuroprotectors
por: Anastassova, Neda, et al.
Publicado: (2023)

In Silico Evaluation and In Vitro Determination of Neuroprotective and MAO-B Inhibitory Effects of Pyrrole-Based Hydrazones: A Therapeutic Approach to Parkinson’s Disease
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2022)

Evaluation of the combined activity of benzimidazole arylhydrazones as new anti-Parkinsonian agents: monoamine oxidase-B inhibition, neuroprotection and oxidative stress modulation
por: Anastassova, Neda, et al.
Publicado: (2021)

Preliminary in vitro evaluation of neuroprotective and monoamine oxidase type B inhibitory effects of newly synthesized 8-aminocaffeines
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2019)

A Comprehensive Evaluation of Sdox, a Promising H(2)S-Releasing Doxorubicin for the Treatment of Chemoresistant Tumors
por: Alov, Petko, et al.
Publicado: (2022)

In situ Gelling Hydroxypropyl Cellulose Formulation Comprising Cannabidiol-Loaded Block Copolymer Micelles for Sustained Drug Delivery
por: Kamenova, Katya, et al.
Publicado: (2023)

Biorenewable Oxypropylated Pentane-1,2,5-triol as a Source for Incorporation in Rigid Polyurethane Foams
por: Grancharov, Georgy, et al.
Publicado: (2023)

Redox-Responsive Crosslinked Mixed Micelles for Controllable Release of Caffeic Acid Phenethyl Ester
por: Kamenova, Katya, et al.
Publicado: (2022)

Doxorubicin and Quercetin Double Loading in Modified MCM-41 Lowered Cardiotoxicity in H9c2 Cardioblast Cells In Vitro
por: Voycheva, Christina, et al.
Publicado: (2023)

Effects of rhamnocitrin 4-β-D-galactopyranoside, isolated from Astragalus hamosus on toxicity models in vitro
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2014)

Thermosensitive Hydrogel-Functionalized Mesoporous Silica Nanoparticles for Parenteral Application of Chemotherapeutics
por: Voycheva, Christina, et al.
Publicado: (2023)

Some In Vitro/In Vivo Chemically-Induced Experimental Models of Liver Oxidative Stress in Rats
por: Simeonova, Rumyana, et al.
Publicado: (2014)

Selective Nitric Oxide Synthase Inhibitor 7-Nitroindazole Protects against Cocaine-Induced Oxidative Stress in Rat Brain
por: Vitcheva, Vessela, et al.
Publicado: (2015)

Flavonoid profiles of three Bupleurum species and in vitro hepatoprotective of activity Bupleurum flavum Forsk.
por: Gevrenova, Reneta, et al.
Publicado: (2015)

Development of Hyphenated Techniques and Network Identification Approaches for Biotransformational Evaluation of Promising Antitubercular N-pyrrolyl hydrazide-hydrazone in Isolated Rat Hepatocytes
por: Mateeva, Alexandrina, et al.
Publicado: (2023)

In Vitro/In Vivo Hepatoprotective and Antioxidant Effects of Defatted Extract and a Phenolic Fraction Obtained from Phlomis Tuberosa
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2023)

Resveratrol-Loaded Chia Seed Oil-Based Nanogel as an Anti-Inflammatory in Adjuvant-Induced Arthritis
por: Afzal, Obaid, et al.
Publicado: (2023)

Multifunctional Polymeric Nanogels for Biomedical Applications
por: Kaewruethai, Tisana, et al.
Publicado: (2021)

Cytoprotective and antioxidant effects of phenolic compounds from Haberlea rhodopensis Friv. (Gesneriaceae)
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2013)

Effects of Aronia melanocarpa Fruit Juice on Isolated Rat Hepatocytes
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2015)

Newly Synthesized Creatine Derivatives as Potential Neuroprotective and Antioxidant Agents on In Vitro Models of Parkinson’s Disease
por: Kostadinova, Ivanka, et al.
Publicado: (2023)

9th International Workshop on Application of Lasers and Storage Devices in Atomic Nuclei Research: Recent Achievements and Future Prospects
por: Marinova, Krassimira, et al.
Publicado: (2014)

11th International Conference on Low Energy Antiproton Physics
por: Marinova, Krassimira, et al.
Publicado: (2014)

Hepatoprotective and Antioxidant Effects of Saponarin, Isolated from Gypsophila trichotoma Wend. on Paracetamol-Induced Liver Damage in Rats
por: Simeonova, Rumyana, et al.
Publicado: (2013)

Quantitative Structure–Neurotoxicity Assessment and In Vitro Evaluation of Neuroprotective and MAO-B Inhibitory Activities of Series N′-substituted 3-(1,3,7-trimethyl-xanthin-8-ylthio)propanehydrazides
por: Kondeva-Burdina, Magdalena, et al.
Publicado: (2022)

Simultaneous analysis of water-soluble and fat-soluble vitamins through RP-HPLC/DAD in food supplements and brewer’s yeast
por: Mateeva, Alexandrina, et al.
Publicado: (2022)

Cycloartane Saponins from Astragalus glycyphyllos and Their In Vitro Neuroprotective, Antioxidant, and hMAO-B-Inhibiting Effects
por: Stambolov, Ivan, et al.
Publicado: (2023)

Ru-Catalyzed Isomerization of Achmatowicz Derivatives: A Sustainable Route to Biorenewables and Bioactive Lactones
por: Dangalov, Miroslav, et al.
Publicado: (2023)

Uniquely sized nanogels via crosslinking polymerization
por: Kusmus, Disraëli N. M., et al.
Publicado: (2022)

Polymeric Nanoparticles and Nanogels: How Do They Interact with Proteins?
por: Sadeghi, Amirhossein, et al.
Publicado: (2023)

Nanocomposite Cryogel Carriers from 2-Hydroxyethyl Cellulose Network and Cannabidiol-Loaded Polymeric Micelles for Sustained Topical Delivery
por: Momekova, Denitsa, et al.
Publicado: (2020)

Polymeric Microneedles for Transdermal Delivery of Rivastigmine: Design and Application in Skin Mimetic Model
por: Guimarães, Tânia M. T., et al.
Publicado: (2022)

Design, Synthesis, In Silico Studies and In Vitro Evaluation of New Indole- and/or Donepezil-like Hybrids as Multitarget-Directed Agents for Alzheimer’s Disease
por: Angelova, Violina T., et al.
Publicado: (2023)

Site-Selective C–H Functionalization of Arenes Enabled by Noncovalent Interactions
por: Fernández-Figueiras, Adolfo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_g3hiobntfpvcuiggiu2l1h95uc