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Efficient and Specific Generation of MSTN-Edited Hu Sheep Using C-CRISPR

Hu sheep, an indigenous breed in China known for its high fecundity, are being studied to improve their growth and carcass traits. MSTN is a negative regulator of muscle development, and its inactivation results in muscularity. The C-CRISPR system, utilizing multiple neighboring sgRNAs targeting a k...

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Detalles Bibliográficos
Autores principales:	Guo, Rihong, Wang, Huili, Meng, Chunhua, Gui, Hongbing, Li, Yinxia, Chen, Fang, Zhang, Chenjian, Zhang, Han, Ding, Qiang, Zhang, Jianli, Zhang, Jun, Qian, Yong, Zhong, Jifeng, Cao, Shaoxian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298037/ https://www.ncbi.nlm.nih.gov/pubmed/37372396 http://dx.doi.org/10.3390/genes14061216

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